Cart
sales@molnova.com
Sulmazole
CAS No. 73384-60-8
Sulmazole( —— )
Catalog No. M34433 CAS No. 73384-60-8
Sulmazole (AR-L 115-BS) is a small molecule Sulmazole is a small molecule cGMP-PDE inhibitor.Sulmazole is a competitive inhibitor of A1 adenosine receptors.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 68 | In Stock |
|
| 10MG | 101 | In Stock |
|
| 25MG | 169 | In Stock |
|
| 50MG | 247 | In Stock |
|
| 100MG | 369 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | 879 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameSulmazole
-
NoteResearch use only, not for human use.
-
Brief DescriptionSulmazole (AR-L 115-BS) is a small molecule Sulmazole is a small molecule cGMP-PDE inhibitor.Sulmazole is a competitive inhibitor of A1 adenosine receptors.
-
DescriptionSulmazole is a cardiotonic agent. Sulmazole has competitive inhibitory for A1 adenosine receptor. Sulmazole can improve cardiac index and reduce pulmonary capillary wedge pressure.
-
In VitroSulmazole has competitive inhibitory for A1 adenosine receptors.Sulmazole attenuates the capacity of GTP to inhibit adenylate cyclase activity and covalent modification of Gi by pertussis toxin treatment abolishes the capacity of sulmazole to mediate stimulation.Sulmazole has stimulatory effect on adenylate cyclase activity in pertussis toxin-treated membranes.Sulmazole mediates increases in cAMP accumulation by mechanisms other than phosphodiesterase inhibition, including A1 adenosine receptor antagonism and inhibition of Gi function.
-
In Vivo——
-
Synonyms——
-
PathwayMicrobiology/Virology
-
TargetParasite
-
RecptorParasite | Adenosine Receptor | PDE
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number73384-60-8
-
Formula Weight287.34
-
Molecular FormulaC14H13N3O2S
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESO(C)C1=C(C=CC(S(C)=O)=C1)C=2NC=3C(N2)=NC=CC3
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. W J Parsons, et al. The new cardiotonic agent sulmazole is an A1 adenosine receptor antagonist and functionally blocks the inhibitory regulator, Gi. Mol Pharmacol. 1988 Apr;33(4):441-8.?
molnova catalog
related products
-
CRK12-IN-2
CRK12-IN-2 is a potent inhibitor of CRK12.CRK12-IN-2 inhibits the parasite, with EC50 values of 3.2 and 0.08 nM for Trypanosoma congolense and Trypanosoma vivax, respectively.
-
2-Benzoxazolinone
2-Benzoxazolol is found in cereals and cereal products. 2-Benzoxazolol is found in rye seedlings.
-
Propargite
Propargite is a pesticide used to kill mites. Propargite induces β-cell necrosis preceded by DNA damage. Propargite induces MIN6 cell death with an IC 50 of 1 μM.
