Nek2-IN-5

CAS No. 1507367-00-1

Nek2-IN-5( —— )

Catalog No. M34342 CAS No. 1507367-00-1

Nek2-IN-5 (NCL00017509) is a potent and selective inhibitor of NIMA-related kinase 2 (Nek2).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 938 In Stock
10MG 1321 In Stock
25MG 1881 In Stock
50MG 2595 In Stock
100MG Get Quote In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Nek2-IN-5
  • Note
    Research use only, not for human use.
  • Brief Description
    Nek2-IN-5 (NCL00017509) is a potent and selective inhibitor of NIMA-related kinase 2 (Nek2).
  • Description
    Nek2-IN-5 (compound 6) is a potent and irreversible Nek2 ((Never in mitosis gene a)-related kinase 2) inhibitior. Nek2-IN-5 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    MAPK/ERK Signaling
  • Target
    p38 MAPK
  • Recptor
    MAPK
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1507367-00-1
  • Formula Weight
    292.3
  • Molecular Formula
    C15H12N6O
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    C(#C)C1=C2C(=NC(NC3=CC(CC(N)=O)=CC=C3)=N1)N=CN2
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Lebraud H, et al. Model system for irreversible inhibition of Nek2: thiol addition to ethynylpurines and related substituted heterocycles. Org Biomol Chem. 2014 Jan 7;12(1):141-8. ?
molnova catalog
related products
  • R1487

    R1487 is an orally bioavailable and highly selective p38α mitogen-activated protein kinase inhibitor.

  • PD 169316

    A potent, selective p38 MAPK inhibitor with IC50 of 89 nM.

  • Kamebakaurine

    Kamebakaurin has the ability to protect the liver from APAP-induced hepatotoxicity, presumably by both inhibiting the inflammatory response and oxidative stress.