Nek2-IN-5( —— )

Catalog No. M34342 CAS No. 1507367-00-1

Nek2-IN-5 (NCL00017509) is a potent and selective inhibitor of NIMA-related kinase 2 (Nek2).

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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Biological Information

Product Name

Nek2-IN-5
Note

Research use only, not for human use.
Brief Description

Nek2-IN-5 (NCL00017509) is a potent and selective inhibitor of NIMA-related kinase 2 (Nek2).
Description

Nek2-IN-5 (compound 6) is a potent and irreversible Nek2 ((Never in mitosis gene a)-related kinase 2) inhibitior. Nek2-IN-5 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

MAPK/ERK Signaling
Target

p38 MAPK
Recptor

MAPK
Research Area

——
Indication

——

Chemical Information

CAS Number

1507367-00-1
Formula Weight

292.3
Molecular Formula

C15H12N6O
Purity

>98% (HPLC)
Solubility

——
SMILES

C(#C)C1=C2C(=NC(NC3=CC(CC(N)=O)=CC=C3)=N1)N=CN2
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Lebraud H, et al. Model system for irreversible inhibition of Nek2: thiol addition to ethynylpurines and related substituted heterocycles. Org Biomol Chem. 2014 Jan 7;12(1):141-8. ?

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