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Olorofim
CAS No. 1928707-56-5
Olorofim( —— )
Catalog No. M34247 CAS No. 1928707-56-5
Olorofim（F-901318）is a novel selective antifungal compound targeting pyrimidine biosynthesis in mycobacteria, with inhibitory effect on Aspergillus fumigatus DHODH (IC50: 44 nM).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 593 | In Stock |
|
| 5MG | 881 | In Stock |
|
| 10MG | 1197 | In Stock |
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| 25MG | 1702 | In Stock |
|
| 50MG | 2098 | In Stock |
|
| 100MG | 2520 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameOlorofim
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NoteResearch use only, not for human use.
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Brief DescriptionOlorofim（F-901318）is a novel selective antifungal compound targeting pyrimidine biosynthesis in mycobacteria, with inhibitory effect on Aspergillus fumigatus DHODH (IC50: 44 nM).
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DescriptionOlorofim（F-901318）is a novel selective antifungal compound targeting pyrimidine biosynthesis in mycobacteria, with inhibitory effect on Aspergillus fumigatus DHODH (IC50: 44 nM), but little inhibitory effect on human DHODH (>100 uM).Olorofim has good efficacy against a variety of pathogenic filamentous and dimorphic fungi, such as Penicillium spp, P. dermatitidis spp and Fusarium spp.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayMetabolic Enzyme/Protease
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TargetDehydrogenase
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RecptorDehydrogenase | Antifungal
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Research Area——
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Indication——
Chemical Information
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CAS Number1928707-56-5
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Formula Weight498.55
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Molecular FormulaC28H27FN6O2
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Purity>98% (HPLC)
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Solubility——
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SMILESC(C(NC1=CC=C(C=C1)N2CCN(CC2)C=3N=CC(F)=CN3)=O)(=O)C4=C(C=C(C)N4C)C5=CC=CC=C5
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
molnova catalog
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