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BPDBA

CAS No. 312281-74-6

BPDBA( —— )

Catalog No. M34193 CAS No. 312281-74-6

BPDBA is an effective, selective, and non-competitive inhibitor of the betaine/GABA transporter (BGT-1), displaying inhibitory activity against human BGT-1 and mouse GAT2, with IC50 values of 20 μM and 35 μM, respectively.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 44 In Stock
10MG 35 In Stock
25MG 74 In Stock
50MG 116 In Stock
100MG 187 In Stock
200MG Get Quote In Stock
500MG 432 In Stock
1G Get Quote In Stock
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Biological Information

  • Product Name
    BPDBA
  • Note
    Research use only, not for human use.
  • Brief Description
    BPDBA is an effective, selective, and non-competitive inhibitor of the betaine/GABA transporter (BGT-1), displaying inhibitory activity against human BGT-1 and mouse GAT2, with IC50 values of 20 μM and 35 μM, respectively.
  • Description
    BPDBA is a selective and noncompetitive betaine/GABA transporter (BGT-1) inhibitor with IC50s of 20 μM and 35 μM against human BGT-1 and mouse GAT2, respectively.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    GABA Receptor
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    312281-74-6
  • Formula Weight
    363.28
  • Molecular Formula
    C19H20Cl2N2O
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (275.27 mM; Ultrasonic )
  • SMILES
    C(N1CCC(NC(=O)C2=C(Cl)C=C(Cl)C=C2)CC1)C3=CC=CC=C3
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Kragholm B, et al. Discovery of a subtype selective inhibitor of the human betaine/GABA transporter 1 (BGT-1) with a non-competitive pharmacological profile. Biochem Pharmacol. 2013 Aug 15;86(4):521-8.?
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