AnnH31

CAS No. 241809-12-1

AnnH31( —— )

Catalog No. M34161 CAS No. 241809-12-1

AnnH31 is a potent Dyrk1A inhibitor with an IC50 value of 81 nM.AnnH31 inhibits MAO-A with an IC50 of 3.2 μM.AnnH31 can be used as a probe to confirm the involvement of DYRK1A in cellular phosphorylation.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 211 In Stock
10MG 294 In Stock
25MG 463 In Stock
50MG 598 In Stock
100MG 768 In Stock
200MG 1023 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    AnnH31
  • Note
    Research use only, not for human use.
  • Brief Description
    AnnH31 is a potent Dyrk1A inhibitor with an IC50 value of 81 nM.AnnH31 inhibits MAO-A with an IC50 of 3.2 μM.AnnH31 can be used as a probe to confirm the involvement of DYRK1A in cellular phosphorylation.
  • Description
    AnnH31 is a Dyrk1A inhibitor (IC50: 81 nM). AnnH31 also inhibits MAO-A with an IC50 of 3.2 μM.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Metabolic Enzyme/Protease
  • Target
    MAO
  • Recptor
    MAO | DYRK
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    241809-12-1
  • Formula Weight
    251.28
  • Molecular Formula
    C15H13N3O
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    C(C#N)N1C=2C(C=3C1=C(C)N=CC3)=CC=C(OC)C2
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Rüben K, et al. Selectivity Profiling and Biological Activity of Novel β-Carbolines as Potent and Selective DYRK1 Kinase Inhibitors. PLoS One. 2015 Jul 20;10(7):e0132453.?
molnova catalog
related products
  • Purpurin

    Purpurin was a reversible and competitive inhibitor of MAO-A with a Ki value of 0.422μM. it exhibits anti-angiogenic antifungal antibiotic and antioxidative activities.

  • Osilodrostat

    Osilodrostat (LCI699) is an effective inhibitor of human 11β-hydroxylase (IC50: 2.5 nM) and aldosterone synthase (IC50: 0.7 nM).

  • Selegiline hydrochlo...

    Selegiline hydrochloride is a selective reversible inhibitor of MAO-B (Ki = 0.091 μM) over MAO-A (Ki = 9.06 μM). Monoamine oxidase (MAO) inhibitors have utility in ameliorating a variety of neurological conditions including depression.