PI3Kδ-IN-3

CAS No. 1431540-99-6

PI3Kδ-IN-3( —— )

Catalog No. M34137 CAS No. 1431540-99-6

PI3Kδ-IN-3 (TC KHNS 11) is a PI3Kδ inhibitor with an IC50 value of 9 nM.PI3Kδ-IN-3 has a favorable pharmacokinetic profile and inhibits B cell function.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 131 Get Quote
5MG 185 Get Quote
10MG 295 Get Quote
25MG 487 Get Quote
50MG 704 Get Quote
100MG 963 Get Quote
500MG 1935 Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    PI3Kδ-IN-3
  • Note
    Research use only, not for human use.
  • Brief Description
    PI3Kδ-IN-3 (TC KHNS 11) is a PI3Kδ inhibitor with an IC50 value of 9 nM.PI3Kδ-IN-3 has a favorable pharmacokinetic profile and inhibits B cell function.
  • Description
    PI3Kδ-IN-3 (Compound 11) is a PI3Kδ inhibitor (IC50: 9 nM). PI3Kδ-IN-3 inhibits B cell function. PI3Kδ-IN-3 has good pharmacokinetic properties.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    PI3K/Akt/mTOR signaling
  • Target
    PI3K
  • Recptor
    PI3K
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1431540-99-6
  • Formula Weight
    492.53
  • Molecular Formula
    C28H24N6O3
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    C(=O)(C=1C=C(C=2C3=C(C=CC(=C3)C=4C=C(C#N)C(OC)=NC4)N=CN2)C=CC1)N5CCN(C(C)=O)CC5
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Hoegenauer K, et al. Discovery and Pharmacological Characterization of Novel Quinazoline-Based PI3K Delta-Selective Inhibitors. ACS Med Chem Lett. 2016 Jun 2;7(8):762-7.?
molnova catalog
related products
  • GSK1016790A

    GSK1016790A (GSK101) is a novel, potent activator of TRPV4 (transient receptor potential vanilloid 4) with EC50 of 34 nM in choroid plexus epithelial cells.

  • Dactolisib

    A potent, dual ATP-competitive pan-class I PI3K and mTOR inhibitor for p110α/γ/δ/β and mTOR(p70S6K) with IC50 of 4 nM /5 nM /7 nM /75 nM /6 nM, respectively.

  • mTOR inhibitor 13

    mTOR inhibitor 13 is a selective mTOR inhibitor with IC50 of 0.29nM and 119nM for mTOR and PI3Kα, respectively.