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VPS34 inhibitor 1 (Compound 19 PIK-III analogue)

CAS No. 1383716-46-8

VPS34 inhibitor 1 (Compound 19 PIK-III analogue)( PIK-III analogue )

Catalog No. M21136 CAS No. 1383716-46-8

VPS34 inhibitor 1 (Compound 19 PIK-III analogue) is a potent and selective inhibitor of VPS34( IC50 : 15 nM).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 154 In Stock
5MG 140 In Stock
10MG 227 In Stock
25MG 398 In Stock
50MG 554 In Stock
100MG 737 In Stock
200MG 1014 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    VPS34 inhibitor 1 (Compound 19 PIK-III analogue)
  • Note
    Research use only, not for human use.
  • Brief Description
    VPS34 inhibitor 1 (Compound 19 PIK-III analogue) is a potent and selective inhibitor of VPS34( IC50 : 15 nM).
  • Description
    VPS34 inhibitor 1 (Compound 19 PIK-III analogue) is a potent and selective inhibitor of VPS34( IC50 : 15 nM).
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    PIK-III analogue
  • Pathway
    PI3K/Akt/mTOR signaling
  • Target
    PI3K
  • Recptor
    Vps34
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1383716-46-8
  • Formula Weight
    391.47
  • Molecular Formula
    C21H25N7O
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:78 mg/mL (199.25 mM)
  • SMILES
    CC(C)(O)CNc1ncc(-c2ccnc(Nc3ccncc3)n2)c(CC2CC2)n1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Honda A Harrington E Cornella-Taracido I et al. Potent Selective and Orally Bioavailable Inhibitors of VPS34 Provide Chemical Tools to Modulate Autophagy in Vivo[J]. ACS Medicinal Chemistry Letters 2015 7(1).
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