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Surfen dihydrochloride
CAS No. 5424-37-3
Surfen dihydrochloride( —— )
Catalog No. M34136 CAS No. 5424-37-3
Surfen dihydrochloride (Aminoquinuride dihydrochloride) is a potent small molecule antagonist of heparin sulfate with antibacterial and antiviral activity.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 81 | Get Quote |
|
| 10MG | 128 | Get Quote |
|
| 25MG | 266 | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
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Biological Information
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Product NameSurfen dihydrochloride
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NoteResearch use only, not for human use.
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Brief DescriptionSurfen dihydrochloride (Aminoquinuride dihydrochloride) is a potent small molecule antagonist of heparin sulfate with antibacterial and antiviral activity.
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DescriptionSurfen dihydrochloride is a potent HS (heparan sulfate) antagonist. Surfen binds to glycosaminoglycans. Surfen neutralizes the anticoagulant activity of both unfractionated and low molecular weight heparins. Surfen affects sulfation of heparin and inhibits degradation by heparin lyases. Surfen inhibits FGF2 binding and signaling. Surfen inhibits cell attachment, and virus infection.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayMicrobiology/Virology
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TargetAntibiotic
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RecptorAntibiotic | FGFR | Antiviral
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Research Area——
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Indication——
Chemical Information
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CAS Number5424-37-3
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Formula Weight445.35
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Molecular FormulaC21H22Cl2N6O
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Purity>98% (HPLC)
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SolubilityIn Vitro:? H2O : 8 mg/mL (17.96 mM)
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SMILESCl.Cl.Cc1cc(N)c2cc(NC(=O)Nc3ccc4nc(C)cc(N)c4c3)ccc2n1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Schuksz M, et al. Surfen, a small molecule antagonist of heparan sulfate. Proc Natl Acad Sci U S A. 2008 Sep 2;105(35):13075-80.?
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