Cart
sales@molnova.com
Home - Products - Microbiology/Virology - Antibiotic - Ormetoprim

Ormetoprim

CAS No. 6981-18-6

Ormetoprim( Ro 5-9754 | Ro-5-9754 | Ro5-9754 )

Catalog No. M27313 CAS No. 6981-18-6

Ormetoprim, an antibiotic approved for use in the United States, is used to prevent the spread of disease in freshwater aquaculture.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 72 In Stock
5MG 38 In Stock
10MG 61 In Stock
25MG 101 In Stock
50MG 144 In Stock
100MG 212 In Stock
200MG Get Quote In Stock
500MG 528 In Stock
1G Get Quote In Stock
Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    Ormetoprim
  • Note
    Research use only, not for human use.
  • Brief Description
    Ormetoprim, an antibiotic approved for use in the United States, is used to prevent the spread of disease in freshwater aquaculture.
  • Description
    Ormetoprim, an antibiotic approved for use in the United States, is used to prevent the spread of disease in freshwater aquaculture.(In Vivo):Ormetoprim (8.3 mg/kg; i.p.) exhibits absorption half-life (5.4 h), elimination half-life (7.5 h) and Cmax (1.2±0.2 μg/mL).Ormetoprim (8.3 mg/kg; p.o.) exhibits absorption half-life (3.9 h), elimination half-life (3.9 h), Cmax (1.6±0.4 μg/mL) and oral availability (78.5%) relative to intraperitoneal administration.
  • In Vitro
    ——
  • In Vivo
    Ormetoprim (8.3 mg/kg; i.p.) exhibits absorption half-life (5.4 h), elimination half-life (7.5 h) and Cmax (1.2±0.2 μg/mL).Ormetoprim (8.3 mg/kg; p.o.) exhibits absorption half-life (3.9 h), elimination half-life (3.9 h), Cmax (1.6±0.4 μg/mL) and oral availability (78.5%) relative to intraperitoneal administration. Animal Model:Hybrid striped bass (565-805 g)Dosage:50 mg/kg Sulfadimethoxine and Ormetoprim in a 5:1 ratio (Pharmacokinetic Analysis)Administration:I.p. and p.o. administration Result:I.p.: t1/2(elim)=7.5 h; t1/2(abs)=5.4 h; Cmax=1.2 μg/mL.P.o.: t1/2(elim)=3.9 h; t1/2(abs)=3.9 h; Cmax=1.6 μg/mL; F=78.5%.
  • Synonyms
    Ro 5-9754 | Ro-5-9754 | Ro5-9754
  • Pathway
    Microbiology/Virology
  • Target
    Antibiotic
  • Recptor
    papain-like protease (PLpro)
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    6981-18-6
  • Formula Weight
    274.324
  • Molecular Formula
    C14H18N4O2
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 25 mg/mL (91.13 mM)
  • SMILES
    COc1cc(C)c(Cc2cnc(N)nc2N)cc1OC
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Ghosh AK, Takayama J, Aubin Y, Ratia K, Chaudhuri R, Baez Y, Sleeman K, Coughlin M, Nichols DB, Mulhearn DC, Prabhakar BS, Baker SC, Johnson ME, Mesecar AD. Structure-based design, synthesis, and biological evaluation of a series of novel and reversible inhibitors for the severe acute respiratory syndrome-coronavirus papain-like protease. J Med Chem. 2009 Aug 27;52(16):5228-40. doi: 10.1021/jm900611t. PMID: 19645480; PMCID: PMC3148848.
Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog
related products

  • Puromycin

    Puromycin is an antibiotic protein synthesis inhibitor. It inhibits protein synthesis by binding to RNA. It also serves as an anticancer drug by suppressing the growth and metastasis in esophagus cancer cells by Akt phosphorylation. It is an antineoplastic and antitrypanosomal agent and is used in research as an inhibitor of protein synthesis.

  • Mtb-IN-2

    Mtb-IN-2 is a small molecule compound of Mycobacterium tuberculosis (Mtb) with antimicrobial activity and low toxicity that interferes with methionine metabolism processes and can be used to study tuberculosis.

  • Trombodipine

    Trombodipine (PCA-4230) is a platelet aggregation inhibitor with antithrombotic activity and protection against Listeria monocytogenes.

Sign In Join Free