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GW438014A
CAS No. 469861-49-2
GW438014A( —— )
Catalog No. M33987 CAS No. 469861-49-2
GW438014A is a potent, selective antagonist of the NPY-Y5 receptor, effectively inhibiting food consumption and curbing body weight gain in obese rodents.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 32 | In Stock |
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| 10MG | 51 | In Stock |
|
| 25MG | 105 | In Stock |
|
| 50MG | 161 | In Stock |
|
| 100MG | 230 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
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Biological Information
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Product NameGW438014A
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NoteResearch use only, not for human use.
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Brief DescriptionGW438014A is a potent, selective antagonist of the NPY-Y5 receptor, effectively inhibiting food consumption and curbing body weight gain in obese rodents.
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DescriptionGW438014A is a potent and selective NPY-Y5 receptor antagonist. GW438014A inhibits food intake and reduces body weight gain in obese rodents.
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In Vitro——
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In VivoAnimal Model:obese ob/ob mice Dosage:10 mg/kg Administration:intraperitoneal injection; daily, for 7 d Result:Decreased the rate of weight gain in both lean and obese rats.
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Synonyms——
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PathwayGPCR/G Protein
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TargetNeuropeptide Y Receptor
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RecptorNeuropeptide Y Receptor
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Research Area——
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Indication——
Chemical Information
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CAS Number469861-49-2
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Formula Weight437.51
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Molecular FormulaC23H23N3O4S
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 250 mg/mL (571.42 mM; Ultrasonic )
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SMILESO=C(NC1=NC=2C=CC=CC2N1CCC=3C=CC=CC3)C=4C=CC=CC4.O=S(=O)(O)C
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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RFRP 3 (human)
Agonist of the NPFF1 receptor (IC50 = 0.7 nM for inhibition of forskolin-induced cAMP production). Homolog of gonadotropin-inhibitory hormone (GnIH); inhibits activity of gonadotropin-releasing hormone (GnRH) neurons.
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Neuropeptide Y (22-3...
Neuropeptide Y (22-36), a 15 amino acid peptide, is a fragment of Neuropeptide Y.Neuropeptide Y (NPY) is a 36 amino-acid neuropeptide that is involved in various physiological and homeostatic processes in both the central and peripheral nervous systems. NPY has been identified as the most abundant peptide present in the mammalian central nervous system, which consists of the brain and spinal cord. It is secreted alongside other neurotransmitters such as GABA and glutamate.
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ML 154
ML 154 is a potent neuropeptide S receptor (NPSR) antagonist.
