Cart
sales@molnova.com
CGP71683 hydrochloride
CAS No. 192322-50-2
CGP71683 hydrochloride( CGP71683A )
Catalog No. M20256 CAS No. 192322-50-2
CGP71683 is a competitive neuropeptide Y5 receptor antagonist (Ki: 1.3 nM) and shows no obvious activity at Y1 receptor (Ki >4000 nM) and Y2 receptor (Ki: 200 nM) in cell membranes.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 113 | In Stock |
|
| 5MG | 102 | In Stock |
|
| 10MG | 154 | In Stock |
|
| 25MG | 256 | In Stock |
|
| 50MG | 361 | In Stock |
|
| 100MG | 528 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameCGP71683 hydrochloride
-
NoteResearch use only, not for human use.
-
Brief DescriptionCGP71683 is a competitive neuropeptide Y5 receptor antagonist (Ki: 1.3 nM) and shows no obvious activity at Y1 receptor (Ki >4000 nM) and Y2 receptor (Ki: 200 nM) in cell membranes.
-
DescriptionCGP71683 is a competitive neuropeptide Y5 receptor antagonist (Ki: 1.3 nM) and shows no obvious activity at Y1 receptor (Ki >4000 nM) and Y2 receptor (Ki: 200 nM) in cell membranes.
-
In VitroCGP71683 hydrochloride is a competitive neuropeptide Y5 receptor antagonist with a Ki of 1.3 nM, and shows no obvious activity at Y1 receptor (Ki, >4000 nM) and Y2 receptor (Ki, 200 nM) in cell membranes.
-
In VivoCGP71683 (15 nmol/rat, icv, twice daily) shows anorexigenic effect, reducing food intake and bady weight of fed rats. CGP71683 causes 3-times higher serum total T4 and 37% increase in free T4 in the fasted rats than in the fasted controls rats.
-
SynonymsCGP71683A
-
PathwayGPCR/G Protein
-
TargetNeuropeptide Y Receptor
-
RecptorY5 receptor
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number192322-50-2
-
Formula Weight512.07
-
Molecular FormulaC26H30ClN5O2S
-
Purity>98% (HPLC)
-
SolubilityDMSO: 120 mg/mL (234.34 mM);Water: 10 mg/mL (19.53 mM)
-
SMILESCl.Nc1nc(NC[C@H]2CC[C@H](CNS(=O)(=O)c3cccc4ccccc34)CC2)nc2ccccc12
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Lecklin A et al. Receptor subtypes Y1 and Y5 mediate neuropeptide Y induced feeding in the guinea-pig. Br J Pharmacol. 2002 Apr;135(8):2029-37.
molnova catalog
related products
-
Galanin (1-29) (rat,...
Non-selective galanin receptor agonist (Ki values are 0.98, 1.48 and 1.47 nM for GAL1, GAL2 and GAL3 respectively). Anticonvulsant; prevents the occurrence of full kindled seizures in rats.
-
Velneperit
Velneperit is potent and selective neuropeptide Y (NPY) Y5 receptor under evaluating for treatment of obesity.
-
L 152804
L 152804 is a specific antagonist of the neuropeptide Y Y5 receptor and modulates food intake and energy expenditure thus causing weight loss in diet-induced obese mice.
