Cart
sales@molnova.com
CAY10444
CAS No. 298186-80-8
CAY10444( —— )
Catalog No. M33970 CAS No. 298186-80-8
CAY10444 is an S1P3 specific antagonist.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 41 | In Stock |
|
| 5MG | 37 | In Stock |
|
| 10MG | 65 | In Stock |
|
| 25MG | 140 | In Stock |
|
| 50MG | 230 | In Stock |
|
| 100MG | 384 | In Stock |
|
| 200MG | 522 | In Stock |
|
| 500MG | 821 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameCAY10444
-
NoteResearch use only, not for human use.
-
Brief DescriptionCAY10444 is an S1P3 specific antagonist.
-
DescriptionCAY10444 (BML-241) is a sphingosine-1-phosphate 3 (S1P3) antagonist. CAY10444 inhibits by 37% S1P-induced increases in Ca2+ in HeLa cells expressing S1P3 receptors.
-
In VitroBML-241 inhibits increases in intracellular Ca2+ concentration via P2 receptor or α1A-adrenoceptor stimulation and α1A-adrenoceptor-mediated contraction of rat mesenteric artery, while it does not affect S1P3-mediated decrease of Forskolin-induced cyclic AMP accumulation.
-
In Vivo——
-
Synonyms——
-
PathwayOthers
-
TargetOther Targets
-
RecptorOthers
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number298186-80-8
-
Formula Weight287.46
-
Molecular FormulaC15H29NO2S
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 41.67 mg/mL (144.96 mM; Ultrasonic (<80°C)
-
SMILESCCCCCCCCCCCC1N[C@@H](CS1)C(O)=O
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Salvatore Salomone, et al. Selectivity and specificity of sphingosine-1-phosphate receptor ligands: caveats and critical thinking in characterizing receptor-mediated effects. Front Pharmacol. 2011 Feb 22;2:9. ?
molnova catalog
related products
-
L-Aspartic acid
Aspartic Acid is a non-essential amino acid in humans, Aspartic Acid has an overall negative charge and plays an important role in the synthesis of other amino acids and in the citric acid and urea cycles.
-
Coumarin-3-carboxyli...
The combination of Valproic acid with coumarin-3-carboxylic acid suppresses the proliferation and migration of lung cancer cells via EGFR/VEGFR2/c-Met-Akt-NF-κB signaling pathways.
-
Lodoxamide
Lodoxamide is an antiallergic drug acting as a mast-cell stabilizer. It is effective in the treatment of asthma and allergic conjunctivitis.
