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Sumatriptan
CAS No. 103628-46-2
Sumatriptan( —— )
Catalog No. M33934 CAS No. 103628-46-2
Sumatriptan (GR 43175 free base) is an orally active and potent 5-hydroxytryptamine 1 (5-HT1) receptor agonist that crosses the blood-brain barrier and has anti-inflammatory activity with high affinity for 5-HT1D, 5-HT1B, and 5-HT1F receptors for use in acute migraines and acute myocardial infarction.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 32 | In Stock |
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| 10MG | 29 | In Stock |
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| 25MG | 43 | In Stock |
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| 50MG | 58 | In Stock |
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| 100MG | 83 | In Stock |
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| 200MG | Get Quote | In Stock |
|
| 500MG | 198 | In Stock |
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| 1G | Get Quote | In Stock |
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Biological Information
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Product NameSumatriptan
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NoteResearch use only, not for human use.
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Brief DescriptionSumatriptan (GR 43175 free base) is an orally active and potent 5-hydroxytryptamine 1 (5-HT1) receptor agonist that crosses the blood-brain barrier and has anti-inflammatory activity with high affinity for 5-HT1D, 5-HT1B, and 5-HT1F receptors for use in acute migraines and acute myocardial infarction.
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DescriptionSumatriptan (GR 43175) is an orally active 5-HT1 receptor agonist with IC50s of 7.3 nm, 9.3nm and 17.8 nm for 5-HT1D, 5-HT1B and 5-HT1F receptors, respectively. Sumatriptan can be used for migraine headache research.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayGPCR/G Protein
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Target5-HT Receptor
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Recptor5-HT Receptor
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Research Area——
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Indication——
Chemical Information
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CAS Number103628-46-2
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Formula Weight295.4
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Molecular FormulaC14H21N3O2S
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (338.52 mM; Ultrasonic )
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SMILESO=S(=O)(NC)CC=1C=CC=2NC=C(C2C1)CCN(C)C
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. S J Peroutka, et al. Sumatriptan (GR 43175) interacts selectively with 5-HT1B and 5-HT1D binding sites. Eur J Pharmacol. 1989 Apr 12;163(1):133-6. ?
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