Cart
sales@molnova.com
PALDA
CAS No. 136181-87-8
PALDA( —— )
Catalog No. M33899 CAS No. 136181-87-8
PALDA (N-Palmitoyl dopamine) is a fatty acid dopamine found in the mammalian brain that is inactive against TRPV1 and inactivates at TRPV(1)R. It is used in the study of duodenal ulcers.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 87 | In Stock |
|
| 10MG | 128 | In Stock |
|
| 25MG | 212 | In Stock |
|
| 50MG | 305 | In Stock |
|
| 100MG | 455 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NamePALDA
-
NoteResearch use only, not for human use.
-
Brief DescriptionPALDA (N-Palmitoyl dopamine) is a fatty acid dopamine found in the mammalian brain that is inactive against TRPV1 and inactivates at TRPV(1)R. It is used in the study of duodenal ulcers.
-
DescriptionN-Palmitoyl dopamine (PALDA) is a endogenous, long-chain, linear fatty acid dopamide, which is inactive on TRPV1. N-Palmitoyl dopamine displays 'entourage' effects on endovanilloids N-arachidonoyl-dopamine (NADA) and anandamide.
-
In VitroPALDA (0.1-10 μM), the EC50 of N-arachidonoyl-dopamine (NADA) is lowered from approximately 90 to approximately 30 nM. The effect on intracellular Ca2+ by another endovanilloid, N-arachidonoyl-ethanolamine (anandamide, 50 nM), is also enhanced dose-dependently by PALDA. PALDA also acted in synergy with low pH (6.0-6.7) to enhance intracellular Ca2+ via TRPV1.
-
In Vivo——
-
Synonyms——
-
PathwayOthers
-
TargetOther Targets
-
RecptorOthers
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number136181-87-8
-
Formula Weight391.59
-
Molecular FormulaC24H41NO3
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESO=C(NCCC1=CC=C(O)C(O)=C1)CCCCCCCCCCCCCCC
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Luciano De Petrocellis, et al. Actions of two naturally occurring saturated N-acyldopamines on transient receptor potential vanilloid 1 (TRPV1) channels. Br J Pharmacol. 2004 Sep;143(2):251-6.?
molnova catalog
related products
-
AU-224
AU-224 is an orally available benzamide derivative that is a potent gastrointestinal prokinetic.
-
NU 9056
NU 9056 is an effective and selective inhibitor of KAT5 histone acetyltransferase with an IC50 of 2 μM. NU 9056 blocks DNA damage response and inhibits protein acetylation in prostate cancer cell lines.
-
N-methyl cinnamamide
N-methyl cinnamamide
