Cart
sales@molnova.com
Home - Products - Others - Other Targets - TAK-448 acetate

TAK-448 acetate

CAS No. 1470374-22-1

TAK-448 acetate( MVT-602 acetate )

Catalog No. M29792 CAS No. 1470374-22-1

TAK-448 is a KISS1R protein agonist as a oligopeptide analog of kisspeptin,TAK-448 acetate (MVT-602 acetate) is a potent and full KISS1R agonist with an IC50 of 460 pM and an EC50 of 632 pM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 235 In Stock
10MG 376 In Stock
25MG 616 In Stock
50MG 848 In Stock
100MG Get Quote In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock
Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    TAK-448 acetate
  • Note
    Research use only, not for human use.
  • Brief Description
    TAK-448 is a KISS1R protein agonist as a oligopeptide analog of kisspeptin,TAK-448 acetate (MVT-602 acetate) is a potent and full KISS1R agonist with an IC50 of 460 pM and an EC50 of 632 pM.
  • Description
    TAK-448 is a KISS1R protein agonist as a oligopeptide analog of kisspeptin,TAK-448 acetate (MVT-602 acetate) is a potent and full KISS1R agonist with an IC50 of 460 pM and an EC50 of 632 pM.(In Vivo):TAK-448 acetate (0.01-3 mg/kg; given i.h.; dosings on day 0 and 28) has greater anti-tumor effects in VCaP xenograft model.
  • In Vitro
    ——
  • In Vivo
    Animal Model:Rat VCaP xenograft androgen-sensitive prostate cancer model (7-week-old rats)Dosage:0.01, 0.03, 0.3, 3 mg/kg Administration:Given i.h.; dosings on day 0 and 28 Result:Had greater anti-tumor effects in VCaP xenograft model.
  • Synonyms
    MVT-602 acetate
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    IC50: 460 pM (KISS1R)
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1470374-22-1
  • Formula Weight
    1285.41
  • Molecular Formula
    C60H84N16O16
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : ≥ 100 mg/mL (77.80 mM)
  • SMILES
    ——
  • Chemical Name
    Sequence:Ac-D-Tyr-D-Trp-Asn-Thr-Phe-azaGly-Leu-Arg(Me)-Trp-NH2

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

Nishizawa N, et al. Design and Synthesis of an Investigational Nonapeptide KISS1 Receptor (KISS1R) Agonist, Ac-d-Tyr-Hydroxyproline (Hyp)-Asn-Thr-Phe-azaGly-Leu-Arg(Me)-Trp-NH2 (TAK-448), with Highly PotentTestosterone-Suppressive Activity and Excellent Water Solubility. J Med Chem. 2016 Oct 13;59(19):8804-8811.
Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog
related products

  • Carasiphenol C

    Carasiphenol C is a natural product from Carex humilis Leyss.

  • DL -34-Dihydroxymand...

    34-Dihydroxymandelic acid is a minor metabolite of norepinephrine in humans. Patients with neuroblastoma experience elevated levels of 34-Dihydroxymandelic acid.

  • Cetrorelix

    Cetrorelix Acetate is gonadotropin-releasing hormone?(GnRH)?receptor antagonist with an?IC50?of 1.21 nM.

Sign In Join Free