Glemanserin( —— )

Catalog No. M33884 CAS No. 107703-78-6

Glemanserin (MDL11939) is a specific 5-HT2A antagonist with Ki values of 0.54 nM, 2.5 nM and 2.89 nM for rabbit, human and rat 5-HT2A.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
1 mL x 10 mM in DMSO	77	In Stock
5MG	76	In Stock
10MG	122	In Stock
25MG	273	In Stock
50MG	423	In Stock
100MG	625	In Stock
200MG	Get Quote	In Stock
500MG	1330	In Stock
1G	Get Quote	In Stock

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Biological Information

Product Name

Glemanserin
Note

Research use only, not for human use.
Brief Description

Glemanserin (MDL11939) is a specific 5-HT2A antagonist with Ki values of 0.54 nM, 2.5 nM and 2.89 nM for rabbit, human and rat 5-HT2A.
Description

Glemanserin (MDL11939) is a potent and selective antagonist for serotonin receptor 5-HT2A (Ki=2.89, 0.54 and 2.5 nM for rat 5-HT2A, rabbit 5-HT2A and human 5-HT2A, respectively).
In Vitro

——
In Vivo

Glemanserin (MDL11939) suppressesthe induced increase in locomotor activity, behavioral sensitization and withdrawal symptoms in male mice.
Synonyms

——
Pathway

GPCR/G Protein
Target

5-HT Receptor
Recptor

5-HT Receptor
Research Area

——
Indication

——

Chemical Information

CAS Number

107703-78-6
Formula Weight

295.42
Molecular Formula

C20H25NO
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 100 mg/mL (338.50 mM; Ultrasonic )
SMILES

OC(C1CCN(CCc2ccccc2)CC1)c1ccccc1
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Pehek EA, et al. Evidence for the preferential involvement of 5-HT2A serotonin receptors in stress- and drug-induced dopamine release in the rat medial prefrontal cortex. Neuropsychopharmacology. 2006;31(2):265-277. ?

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