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Glemanserin

CAS No. 107703-78-6

Glemanserin( —— )

Catalog No. M33884 CAS No. 107703-78-6

Glemanserin (MDL11939) is a specific 5-HT2A antagonist with Ki values of 0.54 nM, 2.5 nM and 2.89 nM for rabbit, human and rat 5-HT2A.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 77 In Stock
5MG 76 In Stock
10MG 122 In Stock
25MG 273 In Stock
50MG 423 In Stock
100MG 625 In Stock
200MG Get Quote In Stock
500MG 1330 In Stock
1G Get Quote In Stock
Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    Glemanserin
  • Note
    Research use only, not for human use.
  • Brief Description
    Glemanserin (MDL11939) is a specific 5-HT2A antagonist with Ki values of 0.54 nM, 2.5 nM and 2.89 nM for rabbit, human and rat 5-HT2A.
  • Description
    Glemanserin (MDL11939) is a potent and selective antagonist for serotonin receptor 5-HT2A (Ki=2.89, 0.54 and 2.5 nM for rat 5-HT2A, rabbit 5-HT2A and human 5-HT2A, respectively).
  • In Vitro
    ——
  • In Vivo
    Glemanserin (MDL11939) suppressesthe induced increase in locomotor activity, behavioral sensitization and withdrawal symptoms in male mice.
  • Synonyms
    ——
  • Pathway
    GPCR/G Protein
  • Target
    5-HT Receptor
  • Recptor
    5-HT Receptor
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    107703-78-6
  • Formula Weight
    295.42
  • Molecular Formula
    C20H25NO
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (338.50 mM; Ultrasonic )
  • SMILES
    OC(C1CCN(CCc2ccccc2)CC1)c1ccccc1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Pehek EA, et al. Evidence for the preferential involvement of 5-HT2A serotonin receptors in stress- and drug-induced dopamine release in the rat medial prefrontal cortex. Neuropsychopharmacology. 2006;31(2):265-277. ?
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