McN-A 343( —— )

Catalog No. M33883 CAS No. 55-45-8

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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Product Name

McN-A 343
Note

Research use only, not for human use.
Brief Description

McN-A 343 is a selective M1 muscarinic agonist known for its ability to stimulate muscarinic transmission in sympathetic ganglia.
Description

McN-A-343 is a selective M1 muscarinic agonist that stimulates muscarinic transmission in sympathetic ganglia. McN-A-343 reduces inflammation and oxidative stress in an experimental model of ulcerative colitis. McN-A-343 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
In Vitro

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In Vivo

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Synonyms

——
Pathway

Cell Cycle/DNA Damage
Target

AChR
Recptor

AChR
Research Area

——
Indication

——

CAS Number

55-45-8
Formula Weight

317.21
Molecular Formula

C14H18Cl2N2O2
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 100 mg/mL (315.25 mM; Ultrasonic )H2O : 100 mg/mL (315.25 mM; Ultrasonic)
SMILES

[Cl-].C[N+](C)(C)CC#CCOC(=O)Nc1cccc(Cl)c1
Chemical Name

——

1. Koss MC, et al. Analysis of miosis produced by McN-A-343 in anesthetized cats. J Ocul Pharmacol Ther. 1995;11(3):389-399. ?

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