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ICI 204,448

CAS No. 121264-04-8

ICI 204,448( —— )

Catalog No. M33869 CAS No. 121264-04-8

ICI 204,448 is a potent κ-opioid agonist with potential analgesic activity for the study of neurological diseases.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    ICI 204,448
  • Note
    Research use only, not for human use.
  • Brief Description
    ICI 204,448 is a potent κ-opioid agonist with potential analgesic activity for the study of neurological diseases.
  • Description
    ICI-204448 is a κ-opioid agonist with limited access to the CNS, ICI-204448 can displace the binding of the kappa-opioid ligand 3H-bremazocine from guinea pig cerebellum membranes.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Endocrinology/Hormones
  • Target
    Opioid Receptor
  • Recptor
    Opioid Receptor
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    121264-04-8
  • Formula Weight
    501.83
  • Molecular Formula
    C23H27Cl3N2O4
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 125 mg/mL (249.09 mM; Ultrasonic )
  • SMILES
    Cl.O=C(O)COC1=CC=CC(=C1)C(N(C(=O)CC2=CC=C(Cl)C(Cl)=C2)C)CN3CCCC3
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. J S Shaw, et, al. ICI 204448: a kappa-opioid agonist with limited access to the CNS. Br J Pharmacol. 1989, 96, 4.?
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