Cart
sales@molnova.com
ICI 204,448
CAS No. 121264-04-8
ICI 204,448( —— )
Catalog No. M33869 CAS No. 121264-04-8
ICI 204,448 is a potent κ-opioid agonist with potential analgesic activity for the study of neurological diseases.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 75 | In Stock |
|
| 10MG | 119 | In Stock |
|
| 25MG | 198 | In Stock |
|
| 50MG | 295 | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameICI 204,448
-
NoteResearch use only, not for human use.
-
Brief DescriptionICI 204,448 is a potent κ-opioid agonist with potential analgesic activity for the study of neurological diseases.
-
DescriptionICI-204448 is a κ-opioid agonist with limited access to the CNS, ICI-204448 can displace the binding of the kappa-opioid ligand 3H-bremazocine from guinea pig cerebellum membranes.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayEndocrinology/Hormones
-
TargetOpioid Receptor
-
RecptorOpioid Receptor
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number121264-04-8
-
Formula Weight501.83
-
Molecular FormulaC23H27Cl3N2O4
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 125 mg/mL (249.09 mM; Ultrasonic )
-
SMILESCl.O=C(O)COC1=CC=CC(=C1)C(N(C(=O)CC2=CC=C(Cl)C(Cl)=C2)C)CN3CCCC3
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. J S Shaw, et, al. ICI 204448: a kappa-opioid agonist with limited access to the CNS. Br J Pharmacol. 1989, 96, 4.?
molnova catalog
related products
-
PL 017
Selective μ opioid receptor agonist (IC50 values are 5.5 and > 10000 nM for inhibition of 125I-FK 33,824 and 125I-DADLE binding to μ and δ sites respectively). Produces naloxone-reversible analgesia, catalepsy and hyperthermia following central administration in rats in vivo.
-
BRL 52537 hydrochlor...
BRL 52537 hydrochloride is a selective and specific KOR agonist which has been implicated in neuroprotection from ischemic neuronal injury.
-
Alvimopan monohydrat...
A selective peripherally acting μ-opioid antagonist with IC50 of 1.7 nM for the treatment of postoperative ileus.
