(E)-FeCP-oxindole

CAS No. 884338-18-5

(E)-FeCP-oxindole( —— )

Catalog No. M33847 CAS No. 884338-18-5

(E)-FeCP-oxindole is an inhibitor of VEGFR2 with IC50 of 214 nM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 102 In Stock
10MG 154 In Stock
25MG 258 In Stock
50MG 359 In Stock
100MG 488 In Stock
200MG 643 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    (E)-FeCP-oxindole
  • Note
    Research use only, not for human use.
  • Brief Description
    (E)-FeCP-oxindole is an inhibitor of VEGFR2 with IC50 of 214 nM.
  • Description
    (Z)-FeCP-oxindole is a selective human vascular endothelial growth factor receptor 2 (VEGFR2) inhibitor with an IC50 value of 200 nM. (Z)-FeCP-oxindole can significantly inhibit VEGFR1 and PDGFRa or b at 10 μM. (Z)-FeCP-oxindole has some anticancer activity, acting on B16 murine melanoma lines with IC50 less than 1 μM.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Angiogenesis
  • Target
    VEGFR
  • Recptor
    VEGFR
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    884338-18-5
  • Formula Weight
    329.17
  • Molecular Formula
    C19H15FeNO
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    C(\[C-]12[Fe+2]3456789([CH]1=[CH]3[CH]4=[CH]52)[CH-]%10[CH]6=[CH]7[CH]8=[CH]9%10)=C/%11\C=%12C(NC%11=O)=CC=CC%12
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. John Spencer, et al. Synthesis and evaluation of metallocene containing methylidene-1,3-dihydro-2H-indol-2-ones as kinase inhibitors. Metallomics. 2011 Jun;3(6):600-8.?
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