4-DAMP

CAS No. 1952-15-4

4-DAMP( —— )

Catalog No. M33823 CAS No. 1952-15-4

4-DAMP (4-DAMP methiodide) is a selective muscarinic M1 and M3 subtype receptor antagonist used in the study of allergic rhinitis and cardiovascular disease.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    4-DAMP
  • Note
    Research use only, not for human use.
  • Brief Description
    4-DAMP (4-DAMP methiodide) is a selective muscarinic M1 and M3 subtype receptor antagonist used in the study of allergic rhinitis and cardiovascular disease.
  • Description
    4-DAMP is a potent antagonist of M3 receptor and also has a high affinity for the closely-related M5 receptor.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    AChR
  • Recptor
    AChR
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1952-15-4
  • Formula Weight
    451.34
  • Molecular Formula
    C21H26INO2
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (221.56 mM; Ultrasonic )
  • SMILES
    [I-].O=C(OC1CC[N+](C)(C)CC1)C(C=2C=CC=CC2)C=3C=CC=CC3
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Watson N, et al. Comparative pharmacology of recombinant human M3 and M5 muscarinic receptors expressed in CHO-K1 cells. Br J Pharmacol. 1999 May;127(2):590-6. ?
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