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Home - Products - Proteasome/Ubiquitin - Endogenous Metabolite - (±)-Propionylcarnitine chloride

(±)-Propionylcarnitine chloride

CAS No. 18828-58-5

(±)-Propionylcarnitine chloride( —— )

Catalog No. M33819 CAS No. 18828-58-5

(±)-Propionylcarnitine chloride (Propionyl-DL-carnitine chloride) is a mixture of short-chain acylcarnitines used as a dietary supplement for the study of chronic diabetes.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    (±)-Propionylcarnitine chloride
  • Note
    Research use only, not for human use.
  • Brief Description
    (±)-Propionylcarnitine chloride (Propionyl-DL-carnitine chloride) is a mixture of short-chain acylcarnitines used as a dietary supplement for the study of chronic diabetes.
  • Description
    Propionyl-DL-carnitine chloride is a carnitine derivative. Propionyl-DL-carnitine chloride can be used for the research of inflammation.
  • In Vitro
    Propionyl-DL-carnitine chloride shows protection to beta-thalassaemic erythrocytes from oxidative stress.Propionyl-DL-carnitine chloride increases production of 14CO2 from [1-14C]pyruvate and increases the rate of formation of acetyl camitine from pyruvate.Propionyl-DL-carnitine chloride allows the endothelial cells to maintain their functionality and regulatory role on vessel activity for a longer time and decreases the formation of oxygen reactive species due to xanthine oxidase activity on hypoxanthine formed by adenine nucleotide catabolism.
  • In Vivo
    Propionyl-DL-carnitine chloride (2 mM/kg; p.o. once daily for 4 weeks) affects plasma and urine total carnitine concentrations of mice.Animal Model:Adult age-matched male C57BL/6 mice Dosage:2 mM/kg Administration: Oral gavage; 2 mM/kg/day for 4 weeks Result:Increased plasma and urine total carnitine concentrations, but showed no effect on the skeletal muscle carnitine content of mice.
  • Synonyms
    ——
  • Pathway
    Proteasome/Ubiquitin
  • Target
    Endogenous Metabolite
  • Recptor
    Endogenous Metabolite
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    18828-58-5
  • Formula Weight
    253.72
  • Molecular Formula
    C10H20ClNO4
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?Methanol : 250 mg/mL (985.34 mM; Ultrasonic)DMSO : 100 mg/mL (394.14 mM; Ultrasonic )
  • SMILES
    [Cl-].CCC(=O)OC(CC(O)=O)C[N+](C)(C)C
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Palmieri L, et al. Protection of beta-thalassaemic erythrocytes from oxidative stress by propionyl carnitine. Int J Tissue React. 1994;16(3):121-9.?
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