(±)-Propionylcarnitine chloride

Research use only, not for human use.

(±)-Propionylcarnitine chloride (Propionyl-DL-carnitine chloride) is a mixture of short-chain acylcarnitines used as a dietary supplement for the study of chronic diabetes.

Propionyl-DL-carnitine chloride is a carnitine derivative. Propionyl-DL-carnitine chloride can be used for the research of inflammation.

Propionyl-DL-carnitine chloride shows protection to beta-thalassaemic erythrocytes from oxidative stress.Propionyl-DL-carnitine chloride increases production of 14CO2 from [1-14C]pyruvate and increases the rate of formation of acetyl camitine from pyruvate.Propionyl-DL-carnitine chloride allows the endothelial cells to maintain their functionality and regulatory role on vessel activity for a longer time and decreases the formation of oxygen reactive species due to xanthine oxidase activity on hypoxanthine formed by adenine nucleotide catabolism.

Propionyl-DL-carnitine chloride (2 mM/kg; p.o. once daily for 4 weeks) affects plasma and urine total carnitine concentrations of mice.Animal Model:Adult age-matched male C57BL/6 mice Dosage:2 mM/kg Administration: Oral gavage; 2 mM/kg/day for 4 weeks Result:Increased plasma and urine total carnitine concentrations, but showed no effect on the skeletal muscle carnitine content of mice.

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Proteasome/Ubiquitin

Endogenous Metabolite

Endogenous Metabolite

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18828-58-5

253.72

C10H20ClNO4

>98% (HPLC)

In Vitro:?Methanol : 250 mg/mL (985.34 mM; Ultrasonic)DMSO : 100 mg/mL (394.14 mM; Ultrasonic )

[Cl-].CCC(=O)OC(CC(O)=O)C[N+](C)(C)C

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(-20℃)

With Ice Pack

≥ 2 years