S-Methylisothiourea sulfate
CAS No. 867-44-7
S-Methylisothiourea sulfate( —— )
Catalog No. M33814 CAS No. 867-44-7
S-Methylisothiourea sulfate ((S)-Methylisothiourea sulfate) is a potent and selective inhibitor of iNOS and exerts beneficial effects in rodent models of septic shock.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 50MG | 31 | In Stock |
|
| 100MG | 45 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | 110 | In Stock |
|
| 1G | 163 | In Stock |
|
Biological Information
-
Product NameS-Methylisothiourea sulfate
-
NoteResearch use only, not for human use.
-
Brief DescriptionS-Methylisothiourea sulfate ((S)-Methylisothiourea sulfate) is a potent and selective inhibitor of iNOS and exerts beneficial effects in rodent models of septic shock.
-
DescriptionS-Methylisothiourea sulfate is a potent, selective and competitive inhibitor of inducible nitric oxide synthase (iNOS). S-Methylisothiourea sulfate exerts beneficial effects in rodent models of septic shock.
-
In Vitro——
-
In VivoAnimal Model:Male Wistar rats (260-320 g)Dosage:0.01 mg/kg, 0.1 mg/kg, 1 mg/kg, 3 mg/kg Administration:Intravenous injection Result:Caused a prompt restoration of the blood pressure to pre-LPS levels at 3 mg/kg dose in LPS (10 mg/kg, i.v.)-treated rats; Inhibited iNOS activity measured in homogenates of lung.
-
Synonyms——
-
PathwayImmunology/Inflammation
-
TargetNOS
-
RecptorNOS | HSV | NO Synthase
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number867-44-7
-
Formula Weight139.18
-
Molecular FormulaC2H6N2S·1/2H2O4S
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?H2O : 65 mg/mL (467.02 mM; Ultrasonic)DMSO : < 1 mg/mL (insoluble or slightly soluble)
-
SMILESCSC(N)=N.CSC(N)=N.OS(O)(=O)=O
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. C Szabó, et al. Beneficial effects and improved survival in rodent models of septic shock with S-methylisothiourea sulfate, a potent and selective inhibitor of inducible nitric oxide synthase. Proc Natl Acad Sci U S A. 1994 Dec 20; 91(26): 12472-12476.?
molnova catalog
related products
-
Stylopine hydrochlor...
Stylopine is a protoberberine-type alkaloid that has potential biological activities including anti-inflammatory activity.
-
Ciwujianoside C3
Ciwujianoside?C3, an orally active and brain penetrated compound, is isolated the leaves of Acanthopanax?henryi Harms. Ciwujianoside?C3 has anti-inflammatory effect and can reinforces object recognition memory.
-
DETA NONOate
DETA NONOate?(NOC 18) is an exogenous nitric oxide (NO) donor with vasodilatory and antidepressant activity.DETA NONOate can be used to activate inward currents in neurons, which may accelerate the healing of MRSA-infected wounds.
Cart
sales@molnova.com