Ciwujianoside C3

Research use only, not for human use.

Ciwujianoside C3, an orally active and brain penetrated compound, is isolated the leaves of Acanthopanax henryi Harms. Ciwujianoside C3 has anti-inflammatory effect and can reinforces object recognition memory.

Ciwujianoside C3 comes from Acanthopanax senticosus.

Cell Viability Assay Cell Line:RAW?264.7 cells Concentration:10 μM, 20 μM and 40?μM Incubation Time:24 hours Result:Has no effect on cell cytotoxicity and inhibits NO production Western Blot Analysis Cell Line:RAW?264.7 cells Concentration:10 μM, 20 μM and 40?μM Incubation Time:24 hours Result:Decreases p-ERK and p-JNK expression. RT-PCR Cell Line:RAW?264.7 cells Concentration:10 μM, 20 μM and 40?μM Incubation Time:24 hours Result:Decreased COX-2 and iNOS mRNA expression in a dose-dependent manner.

Animal Model:Mice Dosage:0.5 mg/kg Administration:Oral administration; 0.5 mg/kg/day; 17 days Result:Reinforced object recognition memory.

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Immunology/Inflammation

NOS

NO Synthase

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114906-74-0

1059.25

C53H86O21

>98% (HPLC)

DMSO : 50 mg/mL (47.20 mM; ultraphonic; )

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(-20℃)

With Ice Pack

≥ 2 years