Arcyriaflavin A

CAS No. 118458-54-1

Arcyriaflavin A( —— )

Catalog No. M33768 CAS No. 118458-54-1

Arcyriaflavin A is derived from Eudistoma sp. It inhibits D1-CDK4, B-CDK1 and CaMKII with IC50 values of 0.14μM, 1.13μM and 0.025μM, respectively.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Arcyriaflavin A
  • Note
    Research use only, not for human use.
  • Brief Description
    Arcyriaflavin A is derived from Eudistoma sp. It inhibits D1-CDK4, B-CDK1 and CaMKII with IC50 values of 0.14μM, 1.13μM and 0.025μM, respectively.
  • Description
    Arcyriaflavin A is a fungal metabolite obtained from the fungi, Nocardiopsis. Arcyriaflavin A is an inhibitor of CDK4 (IC50 = 140 nM) and CaMKII (IC50 = 25 nM).
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Proteasome/Ubiquitin
  • Target
    Endogenous Metabolite
  • Recptor
    Endogenous Metabolite
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    118458-54-1
  • Formula Weight
    325.32
  • Molecular Formula
    C20H11N3O2
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    O=C1NC(=O)C2=C1C1=C(NC3=C1C=CC=C3)C1=C2C2=C(N1)C=CC=C2
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. P A Horton, et al. Staurosporine aglycone (K252-c) and arcyriaflavin A from the marine ascidian, Eudistoma sp. Experientia. 1994 Sep 15;50(9):843-5.?
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