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Oxatomide
CAS No. 60607-34-3
Oxatomide( —— )
Catalog No. M33637 CAS No. 60607-34-3
Oxatomide (Oxatomida) is a potent and orally active dual H1 histamine receptor and P2X7 receptor antagonist with antihistamine and antiallergic activity.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 76 | In Stock |
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| 5MG | 69 | In Stock |
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| 10MG | 117 | In Stock |
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| 25MG | 235 | In Stock |
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| 50MG | 368 | In Stock |
|
| 100MG | 576 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | 1190 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameOxatomide
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NoteResearch use only, not for human use.
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Brief DescriptionOxatomide (Oxatomida) is a potent and orally active dual H1 histamine receptor and P2X7 receptor antagonist with antihistamine and antiallergic activity.
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DescriptionOxatomide is a potent and orally active dual H1-histamine receptor and P2X7 receptor antagonist with antihistamine and anti-allergic activity. Oxatomide almost completely blocks the ATP-induced current in human P2X7 receptors (IC50 of 0.95 μM). Oxatomide inhibits ATP-induced Ca2+ influx with an IC50 value of 0.43 μM and also inhibits serotonin.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayGPCR/G Protein
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Target5-HT Receptor
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Recptor5-HT Receptor | Calcium Channel | P2X Receptor | Histamine Receptor
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Research Area——
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Indication——
Chemical Information
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CAS Number60607-34-3
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Formula Weight426.55
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Molecular FormulaC27H30N4O
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 250 mg/mL (586.10 mM; Ultrasonic )
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SMILESO=C1NC2=C(C=CC=C2)N1CCCN1CCN(CC1)C(C1=CC=CC=C1)C1=CC=CC=C1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Kazuki Yoshida, et al. P2X7 receptor antagonist activity of the anti-allergic agent oxatomide. Eur J Pharmacol. 2015 Nov 15;767:41-51.?
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