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SB 206553
CAS No. 1197334-04-5
SB 206553( SB206553 )
Catalog No. M10703 CAS No. 1197334-04-5
SB 206553 is a potent and selective 5-HT2B/5-HT2C receptor antagonist with pA2 of 8.89 for rat 5-HT2B, pKi of 7.92 for human 5-HT2C, displays >80-fold selectivity over other 5-HT receptor subtypes.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 117 | In Stock |
|
| 10MG | 187 | In Stock |
|
| 25MG | 376 | In Stock |
|
| 50MG | 538 | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
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Biological Information
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Product NameSB 206553
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NoteResearch use only, not for human use.
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Brief DescriptionSB 206553 is a potent and selective 5-HT2B/5-HT2C receptor antagonist with pA2 of 8.89 for rat 5-HT2B, pKi of 7.92 for human 5-HT2C, displays >80-fold selectivity over other 5-HT receptor subtypes.
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DescriptionSB 206553 is a potent and selective 5-HT2B/5-HT2C receptor antagonist with pA2 of 8.89 for rat 5-HT2B, pKi of 7.92 for human 5-HT2C, displays >80-fold selectivity over other 5-HT receptor subtypes; exhibits anxiolytic-like properties both in vitro and in vivo.Anxiety Discontinued.
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In Vitro——
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In Vivo——
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SynonymsSB206553
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PathwayGPCR/G Protein
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Target5-HT Receptor
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Recptor5-HT Receptor
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Research AreaNeurological Disease
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IndicationAnxiety
Chemical Information
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CAS Number1197334-04-5
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Formula Weight328.8
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Molecular FormulaC17H16N4O.HCl
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Purity>98% (HPLC)
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Solubility——
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SMILESO=C(N1C(C(CC1)=C2)=CC3=C2N(C)C=C3)NC4=CC=CN=C4.[H]Cl
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Chemical Name3,5-Dihydro-5-methyl-N-3-pyridinylbenzo[1,2-b:4,5-b']dipyrrole-1(2H)-carboxamide hydrochloride
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Forbes IT, et al. J Med Chem. 1995 Jul 7;38(14):2524-30.
2. Upton N, et al. Eur J Pharmacol. 1998 Oct 16;359(1):33-40.
3. Kennett GA, et al. Br J Pharmacol. 1996 Feb;117(3):427-434.
4. Porras G, et al. Neuropsychopharmacology. 2002 Mar;26(3):311-24.
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