5,6-Dihydrouridine( —— )

Catalog No. M33586 CAS No. 5627-05-4

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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Product Name

5,6-Dihydrouridine
Note

Research use only, not for human use.
Brief Description

5,6-Dihydrouridine, a modified base, is located in conserved positions within the D-loop of tRNA in Eukaryota, Bacteria, and some Archaea.
Description

5,6-Dihydrouridine is a modified base found in conserved positions in the D-loop of tRNA in Bacteria, Eukaryota, and some Archaea.
In Vitro

5,6-Dihydrouridine (Dihydrouridine) is one of the posttranscriptionally modified nucleosides. It is a product of the reduction of uridine (U), and can be further modified to 5-methyldihydrouridine (m5D). 5,6-Dihydrouridine is commonly present in the tRNA from Bacteria, Eukaryota, and some Archaea. It is identified in six positions in the “D-loop” of the tRNA (16, 17, 20a, 20b) and in position 47 in the variable loop.
In Vivo

——
Synonyms

——
Pathway

Proteasome/Ubiquitin
Target

Endogenous Metabolite
Recptor

Endogenous Metabolite
Research Area

——
Indication

——

CAS Number

5627-05-4
Formula Weight

246.22
Molecular Formula

C9H14N2O6
Purity

>98% (HPLC)
Solubility

In Vitro:?H2O : 100 mg/mL (406.14 mM; Ultrasonic)DMSO : 35.71 mg/mL (145.03 mM; Ultrasonic )
SMILES

OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N1CCC(=O)NC1=O
Chemical Name

——

1. Kasprzak JM, et al. Molecular evolution of dihydrouridine synthases. BMC Bioinformatics. 2012 Jun 28;13:153.?

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