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Methyltetrazine-PEG5-NHS ester
CAS No. 1802907-92-1
Methyltetrazine-PEG5-NHS ester( —— )
Catalog No. M33430 CAS No. 1802907-92-1
Methyltetrazine-PEG5-NHS ester is a PROTAC linker belonging to the group of PEGs and is used for the synthesis of PROTAC molecules.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 43 | In Stock |
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| 10MG | 65 | In Stock |
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| 25MG | 117 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameMethyltetrazine-PEG5-NHS ester
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NoteResearch use only, not for human use.
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Brief DescriptionMethyltetrazine-PEG5-NHS ester is a PROTAC linker belonging to the group of PEGs and is used for the synthesis of PROTAC molecules.
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DescriptionMethyltetrazine-PEG5-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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In VitroPROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
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In Vivo——
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Synonyms——
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PathwayPROTACs
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TargetPROTAC
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RecptorPROTAC Linker
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Research Area——
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Indication——
Chemical Information
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CAS Number1802907-92-1
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Formula Weight533.53
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Molecular FormulaC24H31N5O9
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Purity>98% (HPLC)
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Solubility——
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SMILESO=C(ON1C(=O)CCC1=O)CCOCCOCCOCCOCCOC=2C=CC(=CC2)C3=NN=C(N=N3)C
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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CM11
A homo-PROTAC, bivalent small-molecule dimerizer of the VHL E3 ubiquitin ligase to induce self-degradation; induces potent, rapid and proteasome-dependent self-degradation of VHL in different cell lines.
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DBCO-S-S-PEG3-biotin
DBCO-S-S-PEG3-biotin is a cleavable reagent for introduction of a biotin moiety to azide-containing biomolecules using copper-free Click Chemistry.?The disulfide bond in this linker can be cleaved using reducing agents such as DTT, BME and TCEP to remove the biotin label.?PEG Linkers can be used in the synthesis of PROTACs.
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PEG3-methylamine
PEG3-methylamine is a PEG-based linker for PROTACs, joining two essential ligands and facilitating selective protein degradation via the ubiquitin-proteasome system within cells.
