Biotin-PEG8-amine( —— )

Catalog No. M33544 CAS No. 2183447-27-8

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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Product Name

Biotin-PEG8-amine
Note

Research use only, not for human use.
Brief Description

Biotin-PEG8-amine is a PROTAC linker belonging to the PEG class and can be used to synthesize PROTAC molecules.
Description

Biotin-PEG8-amine is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
In Vitro

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
In Vivo

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Synonyms

——
Pathway

Others
Target

Other Targets
Recptor

PROTACs
Research Area

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Indication

——

CAS Number

2183447-27-8
Formula Weight

638.81
Molecular Formula

C28H54N4O10S
Purity

>98% (HPLC)
Solubility

——
SMILES

C(CCCC(NCCOCCOCCOCCOCCOCCOCCOCCOCCN)=O)[C@H]1[C@@]2([C@](CS1)(NC(=O)N2)[H])[H]
Chemical Name

——

1. Gadd MS, et al. Structural basis of PROTAC cooperative recognition for selective protein degradation. Nat Chem Biol. 2017 May;13(5):514-521.?

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