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Buntanetap

CAS No. 116839-68-0

Buntanetap( —— )

Catalog No. M33538 CAS No. 116839-68-0

Buntanetap ((+)-Phenserine) is an orally active inhibitor of polyneurotoxic proteins (TINAPs) for the study of neurological disorders, endocrine and metabolic disorders, and cardiovascular diseases.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Buntanetap
  • Note
    Research use only, not for human use.
  • Brief Description
    Buntanetap ((+)-Phenserine) is an orally active inhibitor of polyneurotoxic proteins (TINAPs) for the study of neurological disorders, endocrine and metabolic disorders, and cardiovascular diseases.
  • Description
    Buntanetap ((+)-Phenserine) is a multiple neurotoxic protein translation inhibitor with oral activity, including amyloid precursor protein (APP), α-synuclein (αSYN) and huntingtin protein (HTT). Buntanetap has anti-inflammatory effects and can be used in the study of Alzheimer's disease and Parkinson's disease.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Membrane Transporter/Ion Channel
  • Target
    Beta Amyloid
  • Recptor
    Beta Amyloid | Huntingtin | AChE
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    116839-68-0
  • Formula Weight
    337.42
  • Molecular Formula
    C20H23N3O2
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 230 mg/mL (681.64 mM; Ultrasonic )
  • SMILES
    C[C@@]12C=3C(N(C)[C@@]1(N(C)CC2)[H])=CC=C(OC(NC4=CC=CC=C4)=O)C3
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Fang C, et al. Buntanetap, a Novel Translational Inhibitor of Multiple Neurotoxic Proteins, Proves to Be Safe and Promising in Both Alzheimer's and Parkinson's Patients. J Prev Alzheimers Dis. 2023;10(1):25-33.?
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