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TY-51469
CAS No. 603987-59-3
TY-51469( —— )
Catalog No. M33525 CAS No. 603987-59-3
TY-51469 is an inhibitor of chymase (IC50s for simian and human chymases: 0.4 and 7.0 nM, respectively).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 67 | In Stock |
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| 2MG | 36 | In Stock |
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| 5MG | 57 | In Stock |
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| 10MG | 103 | In Stock |
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| 25MG | 250 | In Stock |
|
| 50MG | 431 | In Stock |
|
| 100MG | 737 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameTY-51469
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NoteResearch use only, not for human use.
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Brief DescriptionTY-51469 is an inhibitor of chymase (IC50s for simian and human chymases: 0.4 and 7.0 nM, respectively).
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DescriptionTY-51469 is a chymase inhibitor with IC50s for simian and human chymases of 0.4 and 7.0 nM, respectively.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorOthers
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Research Area——
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Indication——
Chemical Information
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CAS Number603987-59-3
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Formula Weight526.6
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Molecular FormulaC20H15FN2O6S4
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 33.33 mg/mL (63.29 mM; Ultrasonic )
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SMILESCc1c(sc2ccc(F)cc12)S(=O)(=O)Nc1ccc(cc1S(C)(=O)=O)-c1nc(cs1)C(O)=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Takato H, et al. The specific chymase inhibitor TY-51469 suppresses the accumulation of neutrophils in the lung and reduces silica-induced pulmonary fibrosis in mice. Expert Opinion on Therapeutic Targets Volume 15, 2011 - Issue 4.
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