Semustine

CAS No. 13909-09-6

Semustine( —— )

Catalog No. M33496 CAS No. 13909-09-6

Semustine, a DNA alkylating agent, is a cancer chemotherapy compound that is nephrotoxic in patients with malignant melanoma receiving adjuvant chemotherapy for the adjuvant treatment of leukemia.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 154 In Stock
10MG 228 In Stock
25MG 390 In Stock
50MG 535 In Stock
100MG 747 In Stock
200MG 1004 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Semustine
  • Note
    Research use only, not for human use.
  • Brief Description
    Semustine, a DNA alkylating agent, is a cancer chemotherapy compound that is nephrotoxic in patients with malignant melanoma receiving adjuvant chemotherapy for the adjuvant treatment of leukemia.
  • Description
    Semustine is a DNA alkylator, binds to DNA, and acts as a cancer chemotherapeutic agent.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    DNA Alkylator/Crosslinker
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    13909-09-6
  • Formula Weight
    247.72
  • Molecular Formula
    C10H18ClN3O2
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (403.68 mM; Ultrasonic ) Ethanol : 50 mg/mL (201.84 mM; Ultrasonic)
  • SMILES
    N(C(N(CCCl)N=O)=O)C1CCC(C)CC1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Agarwal S, et al. Molecular modeling and spectroscopic studies of semustine binding with DNA and its comparison with lomustine-DNA adduct formation. J Biomol Struct Dyn. 2015;33(8):1653-68.?
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