Semustine( —— )

Catalog No. M33496 CAS No. 13909-09-6

Semustine, a DNA alkylating agent, is a cancer chemotherapy compound that is nephrotoxic in patients with malignant melanoma receiving adjuvant chemotherapy for the adjuvant treatment of leukemia.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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10MG	228	In Stock
25MG	390	In Stock
50MG	535	In Stock
100MG	747	In Stock
200MG	1004	In Stock
500MG	Get Quote	In Stock
1G	Get Quote	In Stock

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Biological Information

Product Name

Semustine
Note

Research use only, not for human use.
Brief Description

Semustine, a DNA alkylating agent, is a cancer chemotherapy compound that is nephrotoxic in patients with malignant melanoma receiving adjuvant chemotherapy for the adjuvant treatment of leukemia.
Description

Semustine is a DNA alkylator, binds to DNA, and acts as a cancer chemotherapeutic agent.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Others
Target

Other Targets
Recptor

DNA Alkylator/Crosslinker
Research Area

——
Indication

——

Chemical Information

CAS Number

13909-09-6
Formula Weight

247.72
Molecular Formula

C10H18ClN3O2
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 100 mg/mL (403.68 mM; Ultrasonic ) Ethanol : 50 mg/mL (201.84 mM; Ultrasonic)
SMILES

N(C(N(CCCl)N=O)=O)C1CCC(C)CC1
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Agarwal S, et al. Molecular modeling and spectroscopic studies of semustine binding with DNA and its comparison with lomustine-DNA adduct formation. J Biomol Struct Dyn. 2015;33(8):1653-68.?

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