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Omidenepag

CAS No. 1187451-41-7

Omidenepag( —— )

Catalog No. M33447 CAS No. 1187451-41-7

Omidenepag (UR-7276) is a selective and potent prostaglandin E2 receptor 2 (EP2) agonist and a novel topical ocular hypotensive agent.Omidenepag is used in the study of glaucoma and hypertension.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 93 In Stock
5MG 93 In Stock
10MG 148 In Stock
25MG 302 In Stock
100MG Get Quote In Stock
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Biological Information

  • Product Name
    Omidenepag
  • Note
    Research use only, not for human use.
  • Brief Description
    Omidenepag (UR-7276) is a selective and potent prostaglandin E2 receptor 2 (EP2) agonist and a novel topical ocular hypotensive agent.Omidenepag is used in the study of glaucoma and hypertension.
  • Description
    Omidenepag (UR-7276), a pharmacologically active form of Omidenepag Isopropyl, is a selective, non-prostanoid EP2 receptor agonist, with an EC50 of 1.1 nM. Omidenepag shows binding affinities (IC50) 10 nM for h-EP2.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    GPCR/G Protein
  • Target
    Prostaglandin Receptor
  • Recptor
    Prostaglandin Receptor
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1187451-41-7
  • Formula Weight
    478.52
  • Molecular Formula
    C23H22N6O4S
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 250 mg/mL (522.44 mM; Ultrasonic )
  • SMILES
    OC(=O)CNc1cccc(CN(Cc2ccc(cc2)-n2cccn2)S(=O)(=O)c2cccnc2)n1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Iwamura R, et al. Identification?of a?Selective,?Non-Prostanoid?EP2?Receptor?Agonist?for the?Treatment?of?Glaucoma:?Omidenepag?and its?Prodrug?Omidenepag?Isopropyl. J Med Chem.?2018 Aug 9;61(15):6869-6891.?
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