Cart
sales@molnova.com
NH-bis(PEG3-azide)
CAS No. 1258939-39-7
NH-bis(PEG3-azide)( —— )
Catalog No. M33443 CAS No. 1258939-39-7
NH-bis(PEG3-azide) is a PROTAC linker of the PEG class used in the synthesis of PROTAC molecules.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 39 | In Stock |
|
| 10MG | 55 | In Stock |
|
| 25MG | 95 | In Stock |
|
| 50MG | 138 | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameNH-bis(PEG3-azide)
-
NoteResearch use only, not for human use.
-
Brief DescriptionNH-bis(PEG3-azide) is a PROTAC linker of the PEG class used in the synthesis of PROTAC molecules.
-
DescriptionNH-bis(PEG3-azide) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. NH-bis(PEG3-azide) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
-
In VitroPROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
-
In Vivo——
-
Synonyms——
-
PathwayOthers
-
TargetOther Targets
-
RecptorOthers
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number1258939-39-7
-
Formula Weight419.48
-
Molecular FormulaC16H33N7O6
-
Purity>98% (HPLC)
-
Solubility——
-
SMILES[N-]=[N+]=NCCOCCOCCOCCNCCOCCOCCOCCN=[N+]=[N-]
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562?
molnova catalog
related products
-
Batatasin IV
Batatasin IV is identified from Dioscorea opposita which is a a type of homologous medicinal plant and is commonly used as food in daily life.
-
13-Oxyingenol dodeca...
13-Oxyingenol-dodecanoate (13OD) is a tumor suppressor agent. 13-Oxyingenol-dodecanoate has anti-HIV-1 activity with EC50 value of 33.7 nM.13-Oxyingenol-dodecanoate can induce the expression of ULK1 to effect mitochondrial dysfunction and cellular autophagy. 13-Oxyingenol-dodecanoate also increases the expression of BAX and suppresses the expression of BCL-2 to effect apoptosis.
-
Ganolucidic acid D
Ganolucidic acid D, also known as ganolucidate D, is a triterpenoid.
