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m-PEG8-Ms

CAS No. 1059588-19-0

m-PEG8-Ms( —— )

Catalog No. M33420 CAS No. 1059588-19-0

m-PEG8-Ms is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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10MG 120 In Stock
25MG 188 In Stock
50MG 276 In Stock
100MG 423 In Stock
200MG 622 In Stock
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Biological Information

  • Product Name
    m-PEG8-Ms
  • Note
    Research use only, not for human use.
  • Brief Description
    m-PEG8-Ms is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
  • Description
    m-PEG8-Ms is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. m-PEG8-Ms is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
  • In Vitro
    PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Antibody Drug Conjugates (ADC)
  • Target
    ADCs Linker/Click Chemistry
  • Recptor
    ADC Linker
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1059588-19-0
  • Formula Weight
    462.55
  • Molecular Formula
    C18H38O11S
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    O=S(=O)(OCCOCCOCCOCCOCCOCCOCCOCCOC)C
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Sanxing Sun, et al. Triazolotriazine derivatives as a2a receptor antagonists. WO2020002969A1.
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