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L-Homopropargylglycine
CAS No. 98891-36-2
L-Homopropargylglycine( —— )
Catalog No. M33399 CAS No. 98891-36-2
L-Homopropargylglycine is an alkyl chain-based PROTAC linker utilized in the synthesis of PROTACs.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 28 | In Stock |
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| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
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| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
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Biological Information
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Product NameL-Homopropargylglycine
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NoteResearch use only, not for human use.
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Brief DescriptionL-Homopropargylglycine is an alkyl chain-based PROTAC linker utilized in the synthesis of PROTACs.
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DescriptionL-Homopropargylglycine is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs. L-homopropargylglycine is an amino acid analog of methionine containing an alkyne moiety that can undergo a classic click chemical reaction with azide containing Alexa Fluor.
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In VitroPROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
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In Vivo——
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorOthers
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Research Area——
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Indication——
Chemical Information
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CAS Number98891-36-2
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Formula Weight127.14
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Molecular FormulaC6H9NO2
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 250 mg/mL (1966.34 mM; Ultrasonic )
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SMILESN[C@@H](CCC#C)C(O)=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562?
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