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Fedovapagon
CAS No. 347887-36-9
Fedovapagon( —— )
Catalog No. M33357 CAS No. 347887-36-9
Fedovapagon (VA106483) is a selective and potent agonist of the vasopressin V2 receptor (V2R) that inhibits the growth of intersegmental vessels in zebrafish.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 107 | Get Quote |
|
| 10MG | 170 | Get Quote |
|
| 25MG | 361 | Get Quote |
|
| 50MG | 634 | Get Quote |
|
| 100MG | 876 | Get Quote |
|
| 500MG | Get Quote | Get Quote |
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| 1G | Get Quote | Get Quote |
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Biological Information
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Product NameFedovapagon
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NoteResearch use only, not for human use.
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Brief DescriptionFedovapagon (VA106483) is a selective and potent agonist of the vasopressin V2 receptor (V2R) that inhibits the growth of intersegmental vessels in zebrafish.
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DescriptionFedovapagon (VA106483) is a selective and orally active vasopressin V2 receptor (V2R) agonist with an EC50 of 24 nM. Fedovapagon can be used in the research of nocturia.
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In Vitro——
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In VivoFedovapagon (1 mg/kg, oral administration) inhibits urine output with 81% inhibition rate in rats.Animal Model:Brattleboro rats Dosage:1 mg/kg, 3 mg/kg Administration:Oral administration Result:Reduced urine volume with almost full inhibition of urine output for 2 h.Returned the urine to normal levels 5 h after dosing.
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Synonyms——
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PathwayGPCR/G Protein
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TargetVasopressin Receptor
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RecptorVasopressin Receptor
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Research Area——
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Indication——
Chemical Information
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CAS Number347887-36-9
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Formula Weight462.58
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Molecular FormulaC27H34N4O3
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : ≥ 125 mg/mL (270.22 mM )
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SMILES[H][C@]1(CCCN1C(=O)NCc1ccc(cc1C)C(=O)N1CCCCc2ccccc12)C(=O)N(C)C
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Yea CM, et al.New benzylureas as a novel series of potent, nonpeptidic vasopressin V2 receptor agonists. J Med Chem. 2008 Dec 25;51(24):8124-34.?
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