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CX-157
CAS No. 205187-53-7
CX-157( —— )
Catalog No. M33327 CAS No. 205187-53-7
CX-157 (KP 157) is a novel monoamine oxidase-A (MAO-A) inhibitor for the study of depression-like neurological disorders and cancer.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 246 | In Stock |
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| 5MG | 411 | In Stock |
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| 10MG | 562 | In Stock |
|
| 25MG | 866 | In Stock |
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| 100MG | Get Quote | In Stock |
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| 200MG | Get Quote | In Stock |
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| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
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Biological Information
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Product NameCX-157
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NoteResearch use only, not for human use.
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Brief DescriptionCX-157 (KP 157) is a novel monoamine oxidase-A (MAO-A) inhibitor for the study of depression-like neurological disorders and cancer.
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DescriptionCX-157 is a reversible inhibitor of monoamine oxidase-A (MAO-A) with an EC50 of 19.3 ng/mL.
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In Vitro——
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In VivoCX-157 is a reversible inhibitor of monoamine oxidase-A (MAO-A) with an EC50 of 19.3?ng/mL. CX-157 is an investigational compound currently in development for the treatment of major depressive disorder (MDD). Mechanistic studies in animals have shown that CX-157 acts to inhibit MAO-A activity in a reversible and competitive manner, elevating brain levels of monoamine neurotransmitters.
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Synonyms——
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PathwayMetabolic Enzyme/Protease
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TargetMAO
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RecptorMAO
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Research Area——
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Indication——
Chemical Information
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CAS Number205187-53-7
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Formula Weight348.27
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Molecular FormulaC14H8F4O4S
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Purity>98% (HPLC)
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Solubility——
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SMILESO=S1(=O)C2=CC=C(F)C=C2OC3=CC(OCC(F)(F)F)=CC=C31
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Fowler JS, et al. Reversible inhibitors of monoamine oxidase-A (RIMAs): robust, reversible inhibition of human brain MAO-A by CX157. Neuropsychopharmacology. 2010 Feb;35(3):623-31.?
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