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CB30865
CAS No. 206275-15-2
CB30865( —— )
Catalog No. M33305 CAS No. 206275-15-2
CB30865 (ZM 242421) is a selective and highly effective nicotinamide phosphoribosyltransferase (Nampt) inhibitor with potential antitumor activity.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 500MG | Get Quote | Get Quote |
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| 1G | Get Quote | Get Quote |
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Biological Information
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Product NameCB30865
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NoteResearch use only, not for human use.
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Brief DescriptionCB30865 (ZM 242421) is a selective and highly effective nicotinamide phosphoribosyltransferase (Nampt) inhibitor with potential antitumor activity.
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DescriptionCB30865 (ZM 242421) is a nicotinamide phosphoribosyltransferase (Nampt) inhibitor, with potent cytotoxicity. CB30865 is highly potent against a variety of human tumour cell lines (IC50 values in the 1-10 nM range).
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In VitroCB30865 exhibits cytotoxicity due to NAD reduction via Nampt inhibition.
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In Vivo——
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Synonyms——
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PathwayMetabolic Enzyme/Protease
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TargetNAMPT
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RecptorNAMPT
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Research Area——
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Indication——
Chemical Information
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CAS Number206275-15-2
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Formula Weight516.39
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Molecular FormulaC26H22BrN5O2
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 33.33 mg/mL (64.54 mM; Ultrasonic )
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SMILESO=C1N=C(NC2=CC(Br)=C(C=C12)CN(C3=CC=C(C=C3)C(=O)NCC=4C=NC=CC4)CC#C)C
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Fleischer TC, et al. Chemical proteomics identifies Nampt as the target of CB30865, an orphan cytotoxic compound. Chem Biol. 2010 Jun 25;17(6):659-664.?
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