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HZ-1157
CAS No. 1009734-33-1
HZ-1157( HZ-1157 | HZ 1157 | HZ1157 | Dengue Virus Inhibitor II. )
Catalog No. M17114 CAS No. 1009734-33-1
HZ-1157 is a hepatitis C virus (HCV) inhibitor with inhibitory activities toward HCV NS3/4A protease.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 40 | In Stock |
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| 5MG | 61 | In Stock |
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| 10MG | 98 | In Stock |
|
| 25MG | 186 | In Stock |
|
| 50MG | 295 | In Stock |
|
| 100MG | 478 | In Stock |
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| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameHZ-1157
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NoteResearch use only, not for human use.
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Brief DescriptionHZ-1157 is a hepatitis C virus (HCV) inhibitor with inhibitory activities toward HCV NS3/4A protease.
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DescriptionHZ-1157 is a hepatitis C virus (HCV) inhibitor with inhibitory activities toward HCV NS3/4A protease.
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In VitroHZ-1157 (4a) is known to possess a broad spectrum of biological activities, such as protein lysine methyltransferase G9a inhibition, SMN2 promoter activation, dihydrofolate reductase inhibition, and others.Cell Viability Assay.Cell Line:HZ-1157 (4a) is known to possess a broad spectrum of biological activities, such as protein lysine methyltransferase G9a inhibition, SMN2 promoter activation, dihydrofolate reductase inhibition, and others.Concentration:0-10 μmol/L.Incubation Time:72 h.Result:Inhibited HCV infection in vitro with an IC50 of 0.82 μmol/L.
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In Vivo——
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SynonymsHZ-1157 | HZ 1157 | HZ1157 | Dengue Virus Inhibitor II.
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PathwayMetabolic Enzyme/Protease
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TargetNAMPT
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RecptorHCV NS3/4A protease
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Research Area——
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Indication——
Chemical Information
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CAS Number1009734-33-1
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Formula Weight232.29
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Molecular FormulaC12H16N4O
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 20 mg/mL (86.10 mM)
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SMILESNc1nc(N)c2c(OC(C)(C)C)cccc2n1
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Chemical Name5-(1,1-Dimethylethoxy)- 2,4-quinazolinediamine
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Yu Y, et al. Discovering novel anti-HCV compounds with inhibitory activities toward HCV NS3/4A protease. Acta Pharmacol Sin. 2014 Aug;35(8):1074-81
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