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Resolvin D1
CAS No. 872993-05-0
Resolvin D1( —— )
Catalog No. M33232 CAS No. 872993-05-0
Resolvin D1 (RvD1) is an endogenous pro-inflammatory mediator that blocks pro-inflammatory neutrophil migration by regulating actin polymerization.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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| 100MG | Get Quote | Get Quote |
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| 500MG | Get Quote | Get Quote |
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Biological Information
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Product NameResolvin D1
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NoteResearch use only, not for human use.
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Brief DescriptionResolvin D1 (RvD1) is an endogenous pro-inflammatory mediator that blocks pro-inflammatory neutrophil migration by regulating actin polymerization.
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DescriptionResolvin D1 (RvD1), an endogenous pro-resolving mediator of inflammation, is derived from omega-3 docosahexaenoic acid during the resolution phase of acute inflammation. Resolvin D1 blocks proinflammatory neutrophil migration by regulating actin polymerization, reduces TNF-α–mediated inflammation in macrophages, and enhances phagocytosis of apoptotic cells by macrophages.
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In Vitro——
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In VivoAnimal Model:18-20?g thirty 8-week-old female DBA/1J mice (collagen antibody-induced arthritis (CAIA))Dosage:100, 500, and 1000?ng (or 1000 ng, daily on days 4-10)Administration:i.p. injection; daily on days 10Result:Exhibit a reduced arthritic score.
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Synonyms——
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PathwayApoptosis
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TargetApoptosis
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RecptorApoptosis
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Research Area——
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Indication——
Chemical Information
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CAS Number872993-05-0
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Formula Weight376.49
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Molecular FormulaC22H32O5
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Purity>98% (HPLC)
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Solubility——
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SMILES[C@@H]([C@@H](/C=C/C=C/C=C\C=C\[C@H](C/C=C\CC)O)O)(C/C=C\CCC(O)=O)O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Schmid M, et al. Resolvin D1 Polarizes Primary Human Macrophages toward a Proresolution Phenotype through GPR32. J Immunol. 2016 Apr 15;196(8):3429-37.?
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