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Home - Products - Membrane Transporter/Ion Channel - P2X Receptor - α,β-Methylene ATP trisodium

α,β-Methylene ATP trisodium

CAS No. 1343364-54-4

α,β-Methylene ATP trisodium( —— )

Catalog No. M33198 CAS No. 1343364-54-4

α,β-Methylene ATP trisodium, a phosphonate analog of ATP, is a selective P2X agonist that induces enhanced contraction of UBSM. α,β-Methylene ATP trisodium inhibits P2X1 and P2X3, but is inactive against P2X2, 4 and 7.

Purity : >98% (HPLC)

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Biological Information

  • Product Name
    α,β-Methylene ATP trisodium
  • Note
    Research use only, not for human use.
  • Brief Description
    α,β-Methylene ATP trisodium, a phosphonate analog of ATP, is a selective P2X agonist that induces enhanced contraction of UBSM. α,β-Methylene ATP trisodium inhibits P2X1 and P2X3, but is inactive against P2X2, 4 and 7.
  • Description
    α,β-Methylene-ATP trisodium, a phosphonic analog of ATP, is a P2X3 and P2X7 receptor ligand. α,β-Methylene-ATP trisodium is a highly selective agonist for P2X1 and P2X3, with practically no activity at P2X2,4-7.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Membrane Transporter/Ion Channel
  • Target
    P2X Receptor
  • Recptor
    P2X Receptor
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1343364-54-4
  • Formula Weight
    571.15
  • Molecular Formula
    C11H15N5Na3O12P3
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?H2O : 125 mg/mL (218.86 mM; Ultrasonic)
  • SMILES
    O[C@H]1[C@@H](O[C@@H]([C@H]1O)COP(CP(OP([O-])(O)=O)([O-])=O)([O-])=O)N2C3=NC=NC(N)=C3N=C2.[Na+].[Na+].[Na+]
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Arribas-Blázquez M, et al. Overexpression of P2X3 and P2X7 Receptors and TRPV1 Channels in Adrenomedullary Chromaffin Cells in a Rat Model of Neuropathic Pain. Int J Mol Sci. 2019 Jan 3;20(1).?
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