(S)-Seco-Duocarmycin SA

CAS No. 152785-82-5

(S)-Seco-Duocarmycin SA( —— )

Catalog No. M33115 CAS No. 152785-82-5

(S)-Seco-Duocarmycin SA is a DNA alkylating agent and antibiotic with potent antitumor activity that can be used to synthesize ADC compounds.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    (S)-Seco-Duocarmycin SA
  • Note
    Research use only, not for human use.
  • Brief Description
    (S)-Seco-Duocarmycin SA is a DNA alkylating agent and antibiotic with potent antitumor activity that can be used to synthesize ADC compounds.
  • Description
    (S)-Seco-Duocarmycin SA is a DNA alkylator, cytotoxic to cancer cells, and acts as a ADC cytotoxin for antibody-drug conjugates.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Antibody Drug Conjugates (ADC)
  • Target
    ADC Cytotoxin
  • Recptor
    ADC Cytotoxin | DNA Alkylator/Crosslinker
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    152785-82-5
  • Formula Weight
    513.93
  • Molecular Formula
    C25H24ClN3O7
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    C(Cl)[C@H]1C2=C(N(C(=O)C=3NC=4C(C3)=CC(OC)=C(OC)C4OC)C1)C=C(O)C5=C2C=C(C(OC)=O)N5
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Tichenor MS, et al. Systematic exploration of the structural features of yatakemycin impacting DNA alkylation and biological activity. J Am Chem Soc. 2007 Sep 5;129(35):10858-69.?
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