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ORM-10103
CAS No. 488847-28-5
ORM-10103( —— )
Catalog No. M33047 CAS No. 488847-28-5
ORM-10103 is a novel potent and selective inhibitor of the Na+/Ca2+ exchanger (NCX).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 87 | In Stock |
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| 5MG | 79 | In Stock |
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| 10MG | 130 | In Stock |
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| 25MG | 277 | In Stock |
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| 50MG | 436 | In Stock |
|
| 100MG | 591 | In Stock |
|
| 200MG | 799 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameORM-10103
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NoteResearch use only, not for human use.
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Brief DescriptionORM-10103 is a novel potent and selective inhibitor of the Na+/Ca2+ exchanger (NCX).
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DescriptionORM-10103 is a specific inhibitor of the Na+/Ca2+ exchanger (NCX), which decreases the NCX current with estimated IC50s of 55 and 67 nM at -80 and at 20 mV, respectively.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayGPCR/G Protein
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TargetCalcium Channel
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RecptorCalcium Channel
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Research Area——
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Indication——
Chemical Information
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CAS Number488847-28-5
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Formula Weight348.35
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Molecular FormulaC20H16N2O4
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 250 mg/mL (717.67 mM; Ultrasonic )
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SMILES[O-][N+](=O)c1ccc(Oc2ccc3OC(CCc3c2)c2ccccc2)nc1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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Diltiazem
Diltiazem (CRD 401 free base) is an orally available L-type Ca2+ channel blocker with antihypertensive, antiarrhythmic, and cardioprotective properties that prevent post-reperfusion myocardial injury, angina pectoris, and cardiovascular-related diseases.
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Ticolubant
Ticolubant is orally active leukotriene B4 antagonist with high affinity for the human neutrophil LTB4 receptor (Ki = 0.78 nM), blocks LTB4-induced Ca2+ migration with an IC50 of 6.6 ± 1.5 nM, and shows topical anti-inflammatory activity in a mouse model of skin inflammation.
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N-Desalkylflurazepam
N-Desalkylflurazepam (Norfludiazepam) is a long-acting metabolite of benzodiazepine compounds, such as Flurazepam. N-Desalkylflurazepam inhibits L-type voltage-gated calcium channels with IC 50 values of 55 μM and 37 μM for Ca v 1.2 and Ca v 1.3 , respectively.
