ORM-10103

CAS No. 488847-28-5

ORM-10103( —— )

Catalog No. M33047 CAS No. 488847-28-5

ORM-10103 is a novel potent and selective inhibitor of the Na+/Ca2+ exchanger (NCX).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 87 In Stock
5MG 79 In Stock
10MG 130 In Stock
25MG 277 In Stock
50MG 436 In Stock
100MG 591 In Stock
200MG 799 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    ORM-10103
  • Note
    Research use only, not for human use.
  • Brief Description
    ORM-10103 is a novel potent and selective inhibitor of the Na+/Ca2+ exchanger (NCX).
  • Description
    ORM-10103 is a specific inhibitor of the Na+/Ca2+ exchanger (NCX), which decreases the NCX current with estimated IC50s of 55 and 67 nM at -80 and at 20 mV, respectively.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    GPCR/G Protein
  • Target
    Calcium Channel
  • Recptor
    Calcium Channel
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    488847-28-5
  • Formula Weight
    348.35
  • Molecular Formula
    C20H16N2O4
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 250 mg/mL (717.67 mM; Ultrasonic )
  • SMILES
    [O-][N+](=O)c1ccc(Oc2ccc3OC(CCc3c2)c2ccccc2)nc1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Jost N, et al. ORM-10103, a novel specific inhibitor of the Na+/Ca2+ exchanger, decreases early and delayed afterdepolarizations in the canine heart. Br J Pharmacol. 2013 Oct;170(4):768-78.?
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