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O-Propargyl-Puromycin

CAS No. 1416561-90-4

O-Propargyl-Puromycin( —— )

Catalog No. M33041 CAS No. 1416561-90-4

O-Propargyl-Puromycin (OP-puro) is a potent protein synthesis inhibitor, a puromycin acetylene analog.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 560 In Stock
5MG 511 In Stock
10MG 825 In Stock
25MG 1501 In Stock
50MG 2158 In Stock
100MG Get Quote In Stock
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Biological Information

  • Product Name
    O-Propargyl-Puromycin
  • Note
    Research use only, not for human use.
  • Brief Description
    O-Propargyl-Puromycin (OP-puro) is a potent protein synthesis inhibitor, a puromycin acetylene analog.
  • Description
    O-Propargyl-Puromycin, an alkyne analog of puromycin, is a potent protein synthesis inhibitor. O-Propargyl-Puromycin is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1416561-90-4
  • Formula Weight
    495.53
  • Molecular Formula
    C24H29N7O5
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : ≥ 31 mg/mL (62.56 mM) H2O : < 0.1 mg/mL (insoluble)
  • SMILES
    CN(C)c1ncnc2n(cnc12)[C@@H]1O[C@H](CO)[C@@H](NC(=O)[C@@H](N)Cc2ccc(OCC#C)cc2)[C@H]1O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Liu J, et al. Imaging protein synthesis in cells and tissues with an alkyne analog of puromycin. Proc Natl Acad Sci U S A. 2012 Jan 10;109(2):413-8.?
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