MAPK13-IN-1( —— )

Catalog No. M33008 CAS No. 229002-10-2

MAPK13-IN-1 is a potent MAPK13 (p38δ) inhibitor (IC50: 620 nM).

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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Biological Information

Product Name

MAPK13-IN-1
Note

Research use only, not for human use.
Brief Description

MAPK13-IN-1 is a potent MAPK13 (p38δ) inhibitor (IC50: 620 nM).
Description

MPAK13-IN-1 is a MAPK13 (p38δ) inhibitor, with an IC50 of 620 nM.
In Vitro

Cell Viability Assay Cell Line:Vero E6 cells.Concentration:0-100 μM.Incubation Time:Result:Exhibited an IC50 of 4.63 μM.
In Vivo

——
Synonyms

——
Pathway

MAPK/ERK Signaling
Target

p38 MAPK
Recptor

p38 MAPK
Research Area

——
Indication

——

Chemical Information

CAS Number

229002-10-2
Formula Weight

365.43
Molecular Formula

C20H23N5O2
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : ≥ 250 mg/mL (684.13 mM)
SMILES

Cn1nc(cc1NC(=O)Nc1ccc(Oc2ccncc2)cc1)C(C)(C)C
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Yurtsever Z, et al. First comprehensive structural and biophysical analysis of MAPK13 inhibitors targeting DFG-in and DFG-out binding modes. Biochim Biophys Acta. 2016 Nov;1860(11 Pt A):2335-2344.?

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