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Malic enzyme inhibitor ME1
CAS No. 522649-59-8
Malic enzyme inhibitor ME1( —— )
Catalog No. M33006 CAS No. 522649-59-8
Malic enzyme inhibitor ME1 (ME1) is a specific inhibitor of Malic enzyme (IC50 = 0.15 μM). Malic enzyme inhibitor ME1 reduces cell viability/metabolic activity.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 151 | In Stock |
|
| 5MG | 188 | In Stock |
|
| 10MG | 345 | In Stock |
|
| 25MG | 585 | In Stock |
|
| 50MG | 816 | In Stock |
|
| 100MG | 1097 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | 2223 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameMalic enzyme inhibitor ME1
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NoteResearch use only, not for human use.
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Brief DescriptionMalic enzyme inhibitor ME1 (ME1) is a specific inhibitor of Malic enzyme (IC50 = 0.15 μM). Malic enzyme inhibitor ME1 reduces cell viability/metabolic activity.
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DescriptionMalic enzyme inhibitor ME1 (ME1; compound 1) is a potent inhibitor of Malic enzyme (ME1) with an IC50 of 0.15 μM.
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In VitroCell Viability Assay Cell Line:HCT116 and HT29 cell line Concentration:50 μM Incubation Time:72?hours Result:Showed a significant reduction in total cell numbers.
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In Vivo——
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorOthers
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Research Area——
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Indication——
Chemical Information
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CAS Number522649-59-8
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Formula Weight351.4
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Molecular FormulaC20H21N3O3
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (284.58 mM; Ultrasonic (<60°C)
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SMILESOc1ccc(cc1)N1CCN(CC1)C1CC(=O)N(C1=O)c1ccccc1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Zhang YJ, et al. In silico design and synthesis of piperazine-1-pyrrolidine-2,5-dione scaffold-based novel malic enzyme inhibitors. Bioorg Med Chem Lett. 2006 Feb;16(3):525-8. Epub 2005 Nov 8.?
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