Duoperone( —— )

Catalog No. M32897 CAS No. 62030-88-0

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HNMR

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Product Name

Duoperone
Note

Research use only, not for human use.
Brief Description

Duoperone is a neuroleptic agent. Duoperone shows antiemetic activity in animal models.
Description

Duoperone is a neuroleptic agent and also a antiemetic agent in animal models.
In Vitro

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In Vivo

Duoperone blocks d-amphetamine lethality in mice under aggregated conditions when the pretreatment interval is between one hour and seven days. ABR-6646 produces catalepsy in rats. The onset of this effect is delayed and the duration is prolonged when compared with that of chlorpromazine. Apomorphine-induced pivoting in mice with unilateral lesions of the caudate nucleus is suppressed by ARR-6646.
Synonyms

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Pathway

Others
Target

Other Targets
Recptor

Others
Research Area

——
Indication

——

CAS Number

62030-88-0
Formula Weight

514.58
Molecular Formula

C28H26F4N2OS
Purity

>98% (HPLC)
Solubility

——
SMILES

C(CCN1CCC(C(=O)C2=CC=C(F)C=C2)CC1)N3C=4C(SC=5C3=CC=CC5)=CC=C(C(F)(F)F)C4
Chemical Name

——

1. Johnson DN, et al. AHR-6646: a new, long-acting neuroleptic. Prog Neuropsychopharmacol. 1979;3(5-6):513-20.?

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