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BPR1M97
CAS No. 2059904-66-2
BPR1M97( —— )
Catalog No. M32815 CAS No. 2059904-66-2
BPR1M97 is a mu opioid receptor (MOP) and neuropeptide-orphin FQ (NOP) receptor agonist with blood-brain barrier permeability and potency.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 90 | In Stock |
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| 5MG | 95 | In Stock |
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| 10MG | 151 | In Stock |
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| 25MG | 277 | In Stock |
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| 50MG | 425 | In Stock |
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| 100MG | 598 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameBPR1M97
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NoteResearch use only, not for human use.
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Brief DescriptionBPR1M97 is a mu opioid receptor (MOP) and neuropeptide-orphin FQ (NOP) receptor agonist with blood-brain barrier permeability and potency.
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DescriptionBPR1M97 is a dual-acting mu opioid receptor (MOP) and nociceptin-orphanin FQ peptide (NOP) receptor agonist with Ki values of 1.8 and 4.2 nM, respectively. BPR1M97 shows high potency and blood-brain barrier penetration, and produces potent antinociceptive effects.
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In Vitro——
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In VivoBPR1M97 (1.8 mg/kg; s.c.; once) demonstrates antinociception in a murine model of cancer pain.Animal Model:Male wild-type C57BL/6 mice (25-30?g)Dosage:1.8 mg/kg Administration:Subcutaneous injection (s.c.); once Result:Demonstrated antinociception in a murine model of cancer pain.
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Synonyms——
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PathwayEndocrinology/Hormones
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TargetOpioid Receptor
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RecptorOpioid Receptor
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Research Area——
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Indication——
Chemical Information
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CAS Number2059904-66-2
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Formula Weight349.25
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Molecular FormulaC18H18Cl2N2O
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 250 mg/mL (715.82 mM; Ultrasonic )
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SMILESCN1CCc2ccccc2C1CNC(=O)c1ccc(Cl)c(Cl)c1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Chao PK, et al. BPR1M97, a dual mu opioid receptor/nociceptin-orphanin FQ peptide receptor agonist, producespotent antinociceptive effects with safer properties than morphine. Neuropharmacology. 2019 Jul 3:107678.?
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