Netarsudil mesylate

CAS No. 1422144-42-0

Netarsudil mesylate( —— )

Catalog No. M32785 CAS No. 1422144-42-0

Netarsudil mesylate (AR-13324 mesylate) is a Rho-related protein kinase inhibitor used to study glaucoma and hypertension.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 88 In Stock
5MG 61 In Stock
10MG 107 In Stock
25MG 250 In Stock
50MG 423 In Stock
100MG Get Quote In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Netarsudil mesylate
  • Note
    Research use only, not for human use.
  • Brief Description
    Netarsudil mesylate (AR-13324 mesylate) is a Rho-related protein kinase inhibitor used to study glaucoma and hypertension.
  • Description
    Netarsudil mesylate (AR-13324 mesylate) is a small-molecule inhibitor of Rho kinase and a norepinephrine transporter; reduces intraocular pressure (IOP) in normotensive monkey eyes.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    ROCK
  • Recptor
    ROCK
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1422144-42-0
  • Formula Weight
    645.74
  • Molecular Formula
    C30H35N3O9S2
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (154.86 mM; Ultrasonic )
  • SMILES
    CS(=O)(O)=O.NC[C@H](C1=CC=C(C=C1)COC(C2=C(C=C(C=C2)C)C)=O)C(NC3=CC4=C(C=NC=C4)C=C3)=O.CS(=O)(O)=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Wang RF, et al. Effect of 0.04% AR-13324, a ROCK, and norepinephrine transporter inhibitor, on aqueous humor dynamics in normotensive monkey eyes. J Glaucoma. 2015 Jan;24(1):51-4.?
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