Netarsudil mesylate( —— )

Catalog No. M32785 CAS No. 1422144-42-0

Netarsudil mesylate (AR-13324 mesylate) is a Rho-related protein kinase inhibitor used to study glaucoma and hypertension.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
1 mL x 10 mM in DMSO	88	In Stock
5MG	61	In Stock
10MG	107	In Stock
25MG	250	In Stock
50MG	423	In Stock
100MG	Get Quote	In Stock
200MG	Get Quote	In Stock
500MG	Get Quote	In Stock
1G	Get Quote	In Stock

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Biological Information

Product Name

Netarsudil mesylate
Note

Research use only, not for human use.
Brief Description

Netarsudil mesylate (AR-13324 mesylate) is a Rho-related protein kinase inhibitor used to study glaucoma and hypertension.
Description

Netarsudil mesylate (AR-13324 mesylate) is a small-molecule inhibitor of Rho kinase and a norepinephrine transporter; reduces intraocular pressure (IOP) in normotensive monkey eyes.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Cell Cycle/DNA Damage
Target

ROCK
Recptor

ROCK
Research Area

——
Indication

——

Chemical Information

CAS Number

1422144-42-0
Formula Weight

645.74
Molecular Formula

C30H35N3O9S2
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 100 mg/mL (154.86 mM; Ultrasonic )
SMILES

CS(=O)(O)=O.NC[C@H](C1=CC=C(C=C1)COC(C2=C(C=C(C=C2)C)C)=O)C(NC3=CC4=C(C=NC=C4)C=C3)=O.CS(=O)(O)=O
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Wang RF, et al. Effect of 0.04% AR-13324, a ROCK, and norepinephrine transporter inhibitor, on aqueous humor dynamics in normotensive monkey eyes. J Glaucoma. 2015 Jan;24(1):51-4.?

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