Netarsudil mesylate
CAS No. 1422144-42-0
Netarsudil mesylate( —— )
Catalog No. M32785 CAS No. 1422144-42-0
Netarsudil mesylate (AR-13324 mesylate) is a Rho-related protein kinase inhibitor used to study glaucoma and hypertension.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 88 | In Stock |
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| 5MG | 61 | In Stock |
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| 10MG | 107 | In Stock |
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| 25MG | 250 | In Stock |
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| 50MG | 423 | In Stock |
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| 100MG | Get Quote | In Stock |
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| 200MG | Get Quote | In Stock |
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| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameNetarsudil mesylate
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NoteResearch use only, not for human use.
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Brief DescriptionNetarsudil mesylate (AR-13324 mesylate) is a Rho-related protein kinase inhibitor used to study glaucoma and hypertension.
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DescriptionNetarsudil mesylate (AR-13324 mesylate) is a small-molecule inhibitor of Rho kinase and a norepinephrine transporter; reduces intraocular pressure (IOP) in normotensive monkey eyes.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayCell Cycle/DNA Damage
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TargetROCK
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RecptorROCK
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Research Area——
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Indication——
Chemical Information
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CAS Number1422144-42-0
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Formula Weight645.74
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Molecular FormulaC30H35N3O9S2
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (154.86 mM; Ultrasonic )
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SMILESCS(=O)(O)=O.NC[C@H](C1=CC=C(C=C1)COC(C2=C(C=C(C=C2)C)C)=O)C(NC3=CC4=C(C=NC=C4)C=C3)=O.CS(=O)(O)=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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Y-33075 dihydrochlor...
Y-33075 dihydrochloride is a selective inhibitor of ROCK(IC50 of 3.6 nM).Y-33075 (Y-39983) is a potent inhibitor of ROCK(IC50 of 3.6 nM). Y-33075 also inhibits PKC and CaMKII more potently than Y-27632(IC50s of Y-27632 and Y-33075 for PKC are 9.0 μM and 0.42 μM, respectively), whereas the IC50s of Y-27632 and Y-33075 for CaMKII are 26 μM and 0.81 μM, respectively.
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ROCK-IN-5
ROCK-IN-5 (compound I-B-37) is a potent inhibitor of protein kinases, including ROCK, ERK, GSK, and AGC, with potential applications in cardiac, proliferative, and neurodegenerative disease research.
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H-1152
H-1152 is a potent specific ATP-competitive and cell permeable ROCK inhibitor (Ki = 1.6 nM).
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